PVP1
Poly(vinylpyrrolidone)–Iodine complex
Synonym(s):
PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne® antiseptic
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About This Item
CAS Number:
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
MDL number:
form
powder
Quality Level
solubility
H2O: 100 mg/mL
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, fungi, parasites, viruses, yeast
mode of action
protein synthesis | interferes
SMILES string
II.C=CN1CCCC1=O
InChI
1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
InChI key
CPKVUHPKYQGHMW-UHFFFAOYSA-N
Application
Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.
Biochem/physiol Actions
PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.
Other Notes
An iodophor; "tamed iodine."
Keep container tightly closed in a dry and well-ventilated place.
Legal Information
Povadyne is a registered trademark of National Patent Development Corp.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
>212.0 °F - Not applicable
flash_point_c
> 100 °C - Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A Tuna et al.
Australian dental journal, 57(4), 435-439 (2012-11-29)
The aim of this pilot study was to evaluate the effects of mouthrinses containing 7.5% povidone iodine and 0.2% chlorhexidine on bacteraemia following impacted third molar surgery. Thirty-four patients were enrolled in this study. Patients in the first group were
Lawrence L Yeung et al.
The Journal of urology, 189(1), 136-140 (2012-11-21)
We defined the relevant skin flora during genitourinary prosthetic surgery, evaluated the safety of chlorhexidine-alcohol for use on the male genitalia and compared chlorhexidine-alcohol to povidone-iodine in decreasing the rate of positive bacterial skin cultures at the surgical skin site
Philippe Seguin et al.
Critical care medicine, 42(1), 1-8 (2013-10-10)
To evaluate the efficacy and safety of oral care with povidone-iodine on the occurrence of ventilator-associated pneumonia in a high-risk population. A multicenter, placebo-controlled, randomized, double-blind, two-parallel-group trial performed between May 2008 and May 2011. Six ICUs in France. One
Global Trade Item Number
| SKU | GTIN |
|---|---|
| PVP1-500G | 04061836687137 |
| PVP1-100G | 04061836687120 |
| PVP1-1KG | 04061826757925 |