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PLA0294

Sigma-Aldrich

Goat anti-H2AX Antibody, Affinity Purified

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Synonym(s):
H2A histone family, H2A.X, H2A/X, H2AX, H2AX histone, histone H2A.x, member X
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

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species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:1,000-1:5,000
western blot: 1:1,000- 1:5,000

accession no.

P16104

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

goat ... H2AX(3014)

Immunogen

The epitope recognized by PLA0294 maps to the C-terminus of human Histone H2AX using the numbering given in entry P16104 (GeneID 3014).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability. Gamma H2AX is the phosphorylated form of H2AX that results in response to DNA damage.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

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Andrew M Cobb et al.
Arteriosclerosis, thrombosis, and vascular biology, 41(4), 1339-1357 (2020-12-29)
[Figure: see text].

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