PLA0262
Rabbit anti-Dcp2 Antibody, Affinity Purified
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DCP2 decapping enzyme homolog, DCP2 decapping enzyme homolog (S. cerevisiae), M(7)GpppN-mRNA hydrolase, NUDT20, Nucleoside diphosphate-linked moiety X motif 20, Nudix motif 20, hDpc, mRNA-decapping enzyme 2, nudix (nucleoside diphosphate linked moiety X)-type motif 20
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biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
grade
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species reactivity
human
technique(s)
immunoprecipitation (IP): 5-15 μg/mg
western blot: 1:1,000-1:5,000
accession no.
NP_689837.2
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
rabbit ... Dcp2(167227)
Immunogen
The epitope recognized by PLA0262 maps to a region between residue 370 and 420 of human mRNA-decapping enzyme 2 using the numbering given in entry NP_689837.2 (GeneID 167227).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
mRNA-decapping enzyme 2 (Dcp2) is required for both normal mRNA turnover and nonsense-mediated mRNA decay. Dcp2 plays a role in replication-dependent histone mRNA degradation. It removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5′-phosphorylated mRNA fragment and 7m-GDP [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8IU60].
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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