PLA0232
Rabbit anti-GSK3-beta Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
Synonym(s):
GSK-3 beta, GSK3beta isoform, serine/threonine-protein kinase GSK3B
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
technique(s)
immunoprecipitation (IP): 10 μg/mg, western blot: 1:2,000- 1:10,000
accession no.
AAA66475.1
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
rabbit ... GSK3-beta(2932)
Immunogen
The epitope recognized by PLA0232 maps to a region between residue 1 and 50 of human glycogen synthase kinase-3 beta using the numbering given in entry AAA66475.1 (GeneID 2932).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
Glycogen synthase kinase 3 beta (GSK3beta) is a proline-directed serine-threonine kinase identified as a kinase responsible for the phosphorylation and inactivation of glycogen synthase. GSK3beta is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. In addition to the Wnt-signaling pathway, GSK3beta is also involved in the Hedgehog, Notch and insulin signaling pathways.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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