All Photos(2)
Synonym(s):
CDLS2, DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1, SMC1 (structural maintenance of chromosomes 1; yeast)-like 1, SMC1 structural maintenance of chromosomes 1-like 1 (yeast), SMC1L1, SMC1alpha, Smcb, segregation of mitotic chromosomes 1
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
human, mouse
technique(s)
immunohistochemistry: 1:2,000-1:10,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000
accession no.
NP_006297.2
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
rabbit ... SMC1(8243)
Immunogen
The epitope recognized by PLA0017 maps to a region between residue 1175 and the C-terminus of human Structural Maintenance of Chromosomes 1 using the numbering given in entry NP_006297.2 (GeneID 8243).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
Other Notes
Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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