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PLA0001

Anti-c-Myc Tag Antibody

Name: Anti-c-Myc Tag Antibody
Brand: SIGMA

rabbit polyclonal

Synonym(s):

MRTL, MYCC, avian myelocytomatosis viral oncogene homolog, bHLHe39, c-Myc, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc myelocytomatosis viral oncogene homolog

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

Species reactivity:

human

Technique(s):

ELISA: 1:1,000- 1:30,000, ELISA: 1:100- 1:500 (for coating plates), immunocytochemistry: 1:100-1:400, immunoprecipitation (IP): 1- 4 μg/mg, western blot: 1:1,000- 1:30,000

Application:

ELISA, ICC, IP, WB

Citations:

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Properties

Product Name

Rabbit anti-c-myc Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

human

technique(s)

ELISA: 1:1,000- 1:30,000, ELISA: 1:100- 1:500 (for coating plates), immunocytochemistry: 1:100-1:400, immunoprecipitation (IP): 1- 4 μg/mg, western blot: 1:1,000- 1:30,000

accession no.

NP_002458.2

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... c-myc(4609)

Description

Immunogen

Rabbits were immunized with a synthetic peptide representing amino acid residues 410—419 (EQKLISEEDL) of human myc conjugated to KLH. Antibody was isolated by affinity chromatography using the peptide immobilized on solid support.

Physical form

Phosphate Buffered Saline (PBS) containing 0.09% Sodium Azide

Other Notes

The c-myc epitope tag is a commonly used epitope tag engineered onto the N- or C- terminus of a protein of interest so that the tagged protein can be analyzed and visualized using immunochemical methods. The recognized c-myc epitope represents amino acid residues 410-419, EQKLISEEDL, of human c-myc.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

低风险生物材料

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Sortilin regulates sorting and secretion of Sonic hedgehog.

Charles Campbell et al.

Journal of cell science, 129(20), 3832-3844 (2016-09-17)

Sonic Hedgehog (Shh) is a secreted morphogen that is an essential regulator of patterning and growth. The Shh full-length protein undergoes autocleavage in the endoplasmic reticulum to generate the biologically active N-terminal fragment (ShhN), which is destined for secretion. We

Cancer-Associated Substitutions in RNA Recognition Motifs of PUF60 and U2AF65 Reveal Residues Required for Correct Folding and 3' Splice-Site Selection.

Jana Kralovicova et al.

Cancers, 12(7) (2020-07-16)

U2AF65 (U2AF2) and PUF60 (PUF60) are splicing factors important for recruitment of the U2 small nuclear ribonucleoprotein to lariat branch points and selection of 3' splice sites (3'ss). Both proteins preferentially bind uridine-rich sequences upstream of 3'ss via their RNA

USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination.

Binggong Zhao et al.

Cellular oncology (Dordrecht) (2023-02-03)

Epithelial-to-mesenchymal transition (EMT) is an important cause of high mortality in breast cancer. Twist1 is one of the EMT transcription factors (EMT-TFs) with a noticeably short half-life, which is regulated by proteasome degradation pathways. Recent studies have found that USP13

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Global Trade Item Number

SKU	GTIN
PLA0001-100UG	04061836680954