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Merck
CN

P9641

Nonaethylene glycol monododecyl ether

nonionic surfactant

Synonym(s):

C12E9, Dodecyl nonaethylene glycol ether, Dodecylnonaglycol, Polidocanol, Polyoxyethylene (9) lauryl ether

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About This Item

Linear Formula:
HO(CH2CH2O)9(CH2)11CH3
CAS Number:
3055-99-0
Molecular Weight:
582.81
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24899047
EC Number:
221-284-4
Beilstein/REAXYS Number:
1895308
MDL number:
MFCD00043375

Key Documents

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InChI key

ONJQDTZCDSESIW-UHFFFAOYSA-N

InChI

1S/C30H62O10/c1-2-3-4-5-6-7-8-9-10-11-13-32-15-17-34-19-21-36-23-25-38-27-29-40-30-28-39-26-24-37-22-20-35-18-16-33-14-12-31/h31H,2-30H2,1H3

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

form

liquid

mol wt

micellar average mol wt 64,000

aggregation number

110

CMC

0.08

solubility

water: 100 mg/mL to turbid

density

1,004 g/cm3

Quality Level

200

Related Categories

General description

Nonaethylene glycol monododecyl ether [C12H25O(CH2CH2O)9H] (AEO9) is a non-ionic surfactant.

Application

Nonaethylene glycol monododecyl ether has been used in a study to assess a procedure for analyzing total lipid and triacylglycerol using bovine liver tissue. It has also been used in a study to investigate how particle size of aggregates can be measured by the concentration dependence of the amplitude of the autocorrelation function.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000524595
0000524595
0000515181
0000515181
0000471717

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R J Bick et al.
Archives of biochemistry and biophysics, 286(2), 346-352 (1991-05-01)
When fast twitch skeletal muscle vesicles (SR) and purified calcium pump protein are stripped with the nonionic detergent C12E8 (octaethylene glycol dodecyl ether), not all the membrane phospholipids are removed from the calcium pump protein. Maximal extraction produces a remnant
Y A Mahmmoud et al.
The Journal of biological chemistry, 275(46), 35969-35977 (2000-08-30)
The Na,K-ATPase provides the driving force for many ion transport processes through control of Na(+) and K(+) concentration gradients across the plasma membranes of animal cells. It is composed of two subunits, alpha and beta. In many tissues, predominantly in
Amila Pramisandi et al.
The Journal of general and applied microbiology, 66(5), 273-278 (2020-07-17)
An Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979 was cultured to find novel scaffolds of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors. We obtained altenusin (1), which inhibits PfDHODH, with an IC50 value of 5.9 μM, along with other metabolites: mitorubrinol (2)
Weican Zhang et al.
Langmuir : the ACS journal of surfaces and colloids, 25(4), 2363-2368 (2009-01-24)
In the pH 2.6 and 5.2 systems, soybean peroxidase (SBP) (isoelectric point, pI 3.9) has positive and negative charge, respectively. In order to acquire detailed knowledge on the role played by electrostatics in the denaturation of proteins, a comparison of
Jeffrey T Jensen et al.
Contraception, 94(5), 527-533 (2016-10-25)
Our objective was to conduct a pilot study to determine if transcervical administration of polidocanol foam (PF) with or without doxycycline or benzalkonium chloride (BZK) would prevent pregnancy in baboons. In study phase 1, adult cycling baboons underwent a hysterosalpingogram
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