P9544
Phosphoglucose Isomerase from rabbit muscle
Type XI, lyophilized powder, ≥200 units/mg protein
Synonym(s):
D-Glucose-6-phosphate ketol-isomerase, PGI, Phosphosaccharomutase
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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-603-1
MDL number:
Specific activity:
≥200 units/mg protein
Biological source:
rabbit muscle
biological source
rabbit muscle
type
Type XI
form
lyophilized powder
specific activity
≥200 units/mg protein
composition
protein, 70-100% biuret
storage temp.
−20°C
Quality Level
Application
Phosphoglucose Isomerase (PGI) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. PGI is responsible for the second step of glycolysis and is involved in glucogenesis. It is highly conserved in bacteria and eukaryotes. It is used in sugar assays to convert fructose to glucose . Product 9544 is type XI and is from rabbit muscle. It is useful in enzyme systems requiring low sulfate.
Biochem/physiol Actions
Phosphoglucose Isomerase fuctions as an isomerase, neuroleukin, autocrine motility factor, and a differentiation and maturation mediator . It is responsible for the photosynthetic reduction of carbon.
Physical form
Essentially sulfate-free powder containing citrate buffer salts
Other Notes
One unit will convert 1.0 μmole of D-fructose 6-phosphate to D-glucose 6-phosphate per min at pH 7.4 at 25 °C.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Regulatory Information
低风险生物材料
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B K Campbell et al.
Reproduction (Cambridge, England), 140(5), 721-732 (2010-08-19)
Glucose is a critical metabolic fuel in most mammals although many foodstuffs also contain high levels of the monosaccharides, galactose and fructose. The aims of this work were to determine the insulin response to challenges of these sugars (experiment 1)
Yunfeng Peng et al.
Physiologia plantarum, 148(4), 470-480 (2012-10-16)
Nitrogen (N) limitation reduces leaf growth and photosynthetic rates of maize (Zea mays), and constrains photosynthate translocation to developing ears. Additionally, the period from about 1 week before to 2 weeks after silking is critical for establishing the reproductive sink
C J Jeffery et al.
Biochemistry, 39(5), 955-964 (2000-02-02)
The multifunctional protein phosphoglucose isomerase, also known as neuroleukin, autocrine motility factor, and differentiation and maturation mediator, has different roles inside and outside the cell. In the cytoplasm, it catalyzes the second step in glycolysis. Outside the cell, it serves
Angela Pizzolla et al.
The American journal of pathology, 183(4), 1144-1155 (2013-08-06)
Immunization with human glucose-6-phosphate isomerase (hG6PI) protein or with several of its peptides induces arthritis in DBA/1 mice. We investigated G6PI peptide-induced arthritis in C57BL/10 mice and the effect of oxidative burst on disease. To study the arthritogenicity of G6PI
Sean D Schoville et al.
PloS one, 7(6), e40035-e40035 (2012-07-07)
The marine copepod Tigriopus californicus lives in intertidal rock pools along the Pacific coast, where it exhibits strong, temporally stable population genetic structure. Previous allozyme surveys have found high frequency private alleles among neighboring subpopulations, indicating that there is limited
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