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P9107

Sigma-Aldrich

Anti-Potassium Channel Kv1.3 (Charybdotoxin-Sensitive Voltage-Dependent Potassium Channel, HLK3) antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

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About This Item

MDL number:
MFCD02097210
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat, mouse, human

technique(s)

immunocytochemistry: 1:50 using cells permeabilized with 0.2% Triton X-100
western blot (chemiluminescent): 1:100

UniProt accession no.

P22001

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

Related Categories

Specificity

Recognizes a full-length Kv1.3 protein. Does not cross-react with other potassium channel antigens.

Immunogen

highly purified GST fusion protein from the C-terminal of human potassium channel Kv1.3. The protein corresponds to amino acids 471-523.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Physical form

Lyophilized at ~1 mg/ml from phosphate buffered saline, pH 7.4, containing 5% sucrose, 1% bovine serum albumin, and 0.025% sodium azide.

Preparation Note

Protein A purified.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

含少量动物源组分生物产品
常规特殊物品

Certificates of Analysis (COA)

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Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

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