P9107
Anti-Potassium Channel Kv1.3 (Charybdotoxin-Sensitive Voltage-Dependent Potassium Channel, HLK3) antibody produced in rabbit
IgG fraction of antiserum, lyophilized powder
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About This Item
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rat, mouse, human
technique(s)
immunocytochemistry: 1:50 using cells permeabilized with 0.2% Triton X-100
western blot (chemiluminescent): 1:100
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)
Specificity
Recognizes a full-length Kv1.3 protein. Does not cross-react with other potassium channel antigens.
Immunogen
highly purified GST fusion protein from the C-terminal of human potassium channel Kv1.3. The protein corresponds to amino acids 471-523.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Physical form
Lyophilized at ~1 mg/ml from phosphate buffered saline, pH 7.4, containing 5% sucrose, 1% bovine serum albumin, and 0.025% sodium azide.
Preparation Note
Protein A purified.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
含少量动物源组分生物产品
常规特殊物品
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Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis
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