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Safety Information

P8901

Sigma-Aldrich

Phenyl-Agarose

saline suspension

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MDL number:
UNSPSC Code:
23151817
NACRES:
NA.56

form

saline suspension

Quality Level

matrix

Cross-linked 4% beaded agarose

matrix activation

epoxy

matrix attachment

amino

matrix spacer

12 atoms

capacity

20-50 mg binding capacity (human serum albumin)(per ml of packed gel)
≥4 mg binding capacity (β-lactoglobulin dimer)(per ml of packed gel)

storage temp.

2-8°C

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Application

Phenyl-agarose is used in protein chromatography, affinity chromatography and hydrophobic interactions. Phenyl-agarose has been used to further the understanding of the digestive process of the pest species Dysdercus peruvianus as well as to study early onset dementia and Alzheimer′s disease.

Physical form

Suspension in 0.5 M NaCl containing preservative

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Francisco José Fernández-Gómez et al.
Journal of neuroscience research, 88(1), 155-166 (2009-07-18)
The early-onset, irreversible, severe deficits of learning and memory in the senescence-accelerated mouse (SAM)-prone/8 (SAMP8) support its use as an animal model for human dementias of early onset. Possible implication of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in cognitive dysfunction of
Purification and partial characterization of an aminopeptidase from the midgut tissue of Dysdercus peruvianus
Costa, I.A., et al.
Comp. Biochem. Physiol., B: Comp. Biochem., 158, 235-241 (2011)
Lukasz Bojarski et al.
Clinical chemistry and laboratory medicine, 45(10), 1273-1276 (2007-08-01)
Presenilin 1 (PS1) and presenilin 2 (PS2) are membranous proteins involved in the pathology of Alzheimer's disease. The development of specific therapies targeted at PS1 or PS2 requires the determination of biochemical properties of presenilins. Hence, in this study we

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