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Merck
CN

P8759

Pyrogallol Red

Powder

Synonym(s):

Pyrogallolsulfonephthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12O8S
CAS Number:
Molecular Weight:
400.36
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
251-134-3
MDL number:
Beilstein/REAXYS Number:
61394
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Product Name

Pyrogallol Red, Suitable for use as a complexometric indicator

InChI

1S/C19H12O8S/c20-12-7-5-10-17(15(12)22)26-18-11(6-8-13(21)16(18)23)19(10)9-3-1-2-4-14(9)28(24,25)27-19/h1-8,20-23H

InChI key

KUQNCHZOCSYKOR-UHFFFAOYSA-N

SMILES string

Oc1ccc2c(Oc3c(O)c(O)ccc3C24OS(=O)(=O)c5ccccc45)c1O

form

powder

technique(s)

titration: suitable

color

green to very dark green, and brown

mp

≥300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL, clear

εmax

≥450 at 475 nm in methanol

suitability

suitable for complexometric indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Application

Pyrogallol Red is suitable to prepare Fujita and Watanabe dye reagent used in Pyrogallol Red-Molybdenum (IV) complex (PR) method for the determination and quantification of urinary proteins.

General description

Pyrogallol red (PGR) is an ortho-diphenolic dye. It has high reactivity towards reactive oxygen species (ROS) and reactive nitrogen species (RNS) that include peroxynitrite, radical, peroxyl radicals, hypochlorite & superoxide anion.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Rudolf Pribil
Applied Complexometry: Pergamon Series in Analytical Chemistry null
Jian Sun et al.
Life sciences, 76(24), 2849-2860 (2005-04-06)
In the current study, we compared purified Salvia miltiorrhiza extract (PSME) with Angiotensin-converting enzyme inhibitor, Ramipril, in in vitro experiments and also in vivo using animal model of myocardial infarction. PSME was found to have a significantly higher trolox equivalent
Extent of aminoglycoside interference in the pyrogallol red-molybdate protein assay depends on the concentration of sodium oxalate in the dye reagent
Marshall Thomas
Clinical Chemistry (2004)
K de Leeuw et al.
Journal of critical care, 36, 200-206 (2016-11-05)
In patients with severe burns, resuscitation with large volumes of fluid is needed, partly because of an increase in capillary leakage. Corticosteroids might be beneficial by diminishing capillary leakage. This study aimed to assess in severely burned nonseptic patients whether
K Janšáková et al.
Physiological research, 68(3), 467-479 (2019-03-25)
Thermally processed food contains advanced glycation end products (AGEs) including N(epsilon)-(carboxymethyl)lysine (CML). Higher AGEs or circulating CML were shown to be associated with pregnancy complications such as preeclampsia and gestational diabetes. It is unclear whether this association is causal. The

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