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Merck
CN

P8759

Pyrogallol Red

Powder

Synonym(s):

Pyrogallolsulfonephthalein

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About This Item

Empirical Formula (Hill Notation):
C19H12O8S
CAS Number:
32638-88-3
Molecular Weight:
400.36
NACRES:
NA.47
PubChem Substance ID:
24898975
UNSPSC Code:
12171500
EC Number:
251-134-3
MDL number:
MFCD00005046
Beilstein/REAXYS Number:
61394

Key Documents

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Product Name

Pyrogallol Red, Suitable for use as a complexometric indicator

InChI

1S/C19H12O8S/c20-12-7-5-10-17(15(12)22)26-18-11(6-8-13(21)16(18)23)19(10)9-3-1-2-4-14(9)28(24,25)27-19/h1-8,20-23H

InChI key

KUQNCHZOCSYKOR-UHFFFAOYSA-N

SMILES string

Oc1ccc2c(Oc3c(O)c(O)ccc3C24OS(=O)(=O)c5ccccc45)c1O

form

powder

technique(s)

titration: suitable

color

green to very dark green, and brown

mp

≥300 °C (lit.)

solubility

1 M NH4OH: 10 mg/mL, clear

εmax

≥450 at 475 nm in methanol

suitability

suitable for complexometric indicator

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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General description

Pyrogallol red (PGR) is an ortho-diphenolic dye. It has high reactivity towards reactive oxygen species (ROS) and reactive nitrogen species (RNS) that include peroxynitrite, radical, peroxyl radicals, hypochlorite & superoxide anion.

Application

Pyrogallol Red is suitable to prepare Fujita and Watanabe dye reagent used in Pyrogallol Red-Molybdenum (IV) complex (PR) method for the determination and quantification of urinary proteins.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000532593
0000532593
0000499863
0000499863
0000476590

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Molecules-Kinetics of the Reaction of Pyrogallol Red, a Polyphenolic Dye, with Nitrous Acid: Role of NO and NO2
Molecules (Basel) null
Tomoko Usui et al.
Clinical and experimental nephrology, 24(2), 151-156 (2019-11-18)
Urine dipstick tests are often used to evaluate proteinuria during health checkups. We examined the dipstick's accuracy in assessing the proteinuria levels among Japanese workers. We assessed subjects aged ≥ 18 years who had a health checkup at the University of Tokyo in
Juan David Figueroa et al.
Redox biology, 24, 101207-101207 (2019-05-19)
Carbonate radicals (CO3-) are generated by the bicarbonate-dependent peroxidase activity of cytosolic superoxide dismutase (Cu,Zn-SOD, SOD-1). The present work explored the use of bleaching of pyrogallol red (PGR) dye to quantify the rate of CO3- formation from bovine and human
Piyali Chatterjee et al.
PloS one, 7(7), e41884-e41884 (2012-08-01)
Preeclampsia (PE) is a pregnancy-specific hypertensive syndrome characterized by excessive maternal immune system activation, inflammation, and endothelial dysfunction. Toll-like receptor (TLR) 3 activation by double-stranded RNA (dsRNA) and TLR7/8 activation by single-stranded RNA (ssRNA) expressed by viruses and/or released from
Randolph B Caldwell et al.
Applied and environmental microbiology, 70(1), 610-612 (2004-01-09)
A simple and reliable method for precipitating protein from bacterial culture supernatants based on a pyrogallol red-molybdate-methanol (PRMM) protocol has been developed and applied for the analysis of proteins secreted by a bacterial type III secretion system. PRMM-based precipitation has
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