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Safety Information

P8650

Sigma-Aldrich

Prednisolone 21-acetate

≥97%

Synonym(s):

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate, 11β,17α,21-Trihydroxy-1,4-pregnadiene-3,20-dione 21-acetate, 21-Acetoxy-1,4-pregnadiene-11β,17α-diol-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C23H30O6
CAS Number:
52-21-1
Molecular Weight:
402.48
Beilstein:
3111798
EC Number:
200-134-1
MDL number:
MFCD00037710
UNSPSC Code:
12352200
PubChem Substance ID:
24898962
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

100

sterility

non-sterile

Assay

≥97%

form

powder

solubility

chloroform: methanol (1:1): 50 mg/mL, clear, colorless

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h6,8,10,16-18,20,26,28H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key

LRJOMUJRLNCICJ-JZYPGELDSA-N

Gene Information

human ... NR3C1(2908)

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Related Categories

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360FD

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR0800
MKCQ6853
MKCL7577
MKCL5230
MKCL1739

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Namrata Sharma et al.
Cornea, 34(9), 1170-1174 (2015-06-27)
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Rohit Shetty et al.
American journal of ophthalmology, 159(3), 419-425 (2014-12-03)
To evaluate the effect of keratoconus cone location on the change in refractive outcomes, corneal aberrations, and biomechanics after combined topography-guided photorefractive keratectomy (PRK) and collagen cross-linking (CXL). Prospective, comparative case series. Topography-guided PRK was performed followed by accelerated CXL
Stephen S Lane et al.
Journal of cataract and refractive surgery, 39(2), 168-173 (2012-12-13)
To evaluate the efficacy of loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the control of postoperative inflammation in patients having routine cataract surgery. Private practice, Stillwater, Minnesota, and Cincinnati Eye Institute, Cincinnati, Ohio, USA. Comparative case series. Patients were
Salima I Hassanaly et al.
American journal of ophthalmology, 158(2), 270-276 (2014-05-23)
To describe outcomes after Boston Type 1 Keratoprosthesis (KPro) surgery in aniridic eyes. Retrospective, interventional case series. University-based tertiary care institution. Twenty-six aniridic eyes of 19 patients who underwent KPro implantation by a single experienced surgeon (M.H.-D.) between October 27
Marcus Ang et al.
American journal of ophthalmology, 157(6), 1163-1169 (2014-03-04)
To compare 3-year endothelial cell loss and graft survival following Descemet stripping automated endothelial keratoplasty (DSAEK) using the EndoGlide (AngioTech, Reading, Pennsylvania, USA/Network Medical Products, North Yorkshire, UK) donor insertion device compared to donor insertion using the Sheets glide technique.
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