P8102
PAPA NONOate
Synonym(s):
3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15
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About This Item
Empirical Formula (Hill Notation):
C6H16N4O2
CAS Number:
Molecular Weight:
176.22
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CCCN(CCCCN)N(O)N=O
shipped in
dry ice
storage temp.
−70°C
General description
NO donor
Biochem/physiol Actions
NO release: t1/2 = 77 min (phosphate buffer at 22 °C)
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C M Maragos et al.
Cancer research, 53(3), 564-568 (1993-02-01)
Cell-mediated antitumor effects have, in part, been attributed to the production of NO. Compounds which generate NO might, therefore, be useful in attenuating the growth of tumor cells. Six nitric oxide/nucleophile adducts that release NO spontaneously in solution were tested
Hrabie, J.A., et al.
The Journal of Organic Chemistry, 58, 1472-1472 (1993)
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