P8102
PAPA NONOate
Synonym(s):
3-(2-Hydroxy-2-nitroso-1-propylhydrazino)-1-propanamine, NOC-15
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About This Item
Empirical Formula (Hill Notation):
C6H16N4O2
CAS Number:
Molecular Weight:
176.22
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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shipped in
dry ice
storage temp.
−70°C
SMILES string
CCCN(CCCCN)N(O)N=O
General description
NO donor
Biochem/physiol Actions
NO release: t1/2 = 77 min (phosphate buffer at 22 °C)
Signal Word
Warning
Hazard Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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C M Maragos et al.
Cancer research, 53(3), 564-568 (1993-02-01)
Cell-mediated antitumor effects have, in part, been attributed to the production of NO. Compounds which generate NO might, therefore, be useful in attenuating the growth of tumor cells. Six nitric oxide/nucleophile adducts that release NO spontaneously in solution were tested
Hrabie, J.A., et al.
The Journal of Organic Chemistry, 58, 1472-1472 (1993)
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