P7780
Propionylpromazine hydrochloride
Synonym(s):
Propiopromazine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C20H24N2OS · HCl
CAS Number:
Molecular Weight:
376.94
Beilstein:
38502
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
form
powder
Quality Level
storage temp.
2-8°C
SMILES string
Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1
InChI
1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H
InChI key
ZFWVWZODBGTOIL-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813)
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Biochem/physiol Actions
Phenothiazine antipsychotic; D2 dopamine receptor antagonist.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives.
FAO food and nutrition paper, 41(4), 1-136 (1991-01-01)
J Park et al.
Journal of chromatography, 489(2), 313-321 (1989-04-14)
The propionylpromazine concentrations in plasma after intramuscular administration to horses were determined using gas chromatography with nitrogen-phosphorus detection. After hydrolysis by beta-glucuronidase/arylsulphatase, the parent drug and three metabolites were detected in urine. The metabolites were identified as 2-(1-hydroxypropyl)promazine, 2-(1-propenyl)promazine and
[The opinion of O. Habler].
O Habler
Der Anaesthesist, 50(8), 613-614 (2001-09-15)
[Effects and side effects of some combinations of often used tranquillizers for sedation in horses].
W Rohr et al.
DTW. Deutsche tierarztliche Wochenschrift, 89(7), 262-267 (1982-07-06)
[Acute normovolemic hemodilution (ANH). Der Anaesthesist (2000) 49: 939-948].
M Alef
Der Anaesthesist, 50(8), 612-613 (2001-09-15)
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