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P7627

Sigma-Aldrich

6-Phosphogluconic acid barium salt hydrate

Grade VI, ≥90%, powder

Synonym(s):

6-PG-Ba, D-Gluconate 6-phosphate barium salt

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About This Item

Empirical Formula (Hill Notation):
C6H10Ba1.5O10P · xH2O
CAS Number:
921-62-0
Molecular Weight:
479.10 (anhydrous basis)
Beilstein:
1729373
EC Number:
213-069-9
UNSPSC Code:
12352201
PubChem Substance ID:
24898864
NACRES:
NA.25

biological source

synthetic (organic)

type

Grade VI

Assay

≥90%

form

powder

color

white

storage temp.

−20°C

SMILES string

[O-]P(OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O)([O-])=O.[H]O[H].C

InChI

1S/C6H13O10P.CH4.H2O/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);1H4;1H2/p-3/t2-,3-,4+,5-;;/m1../s1

InChI key

VINGHIAQWNFZIR-ZBHRUSISSA-K

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General description

suitable for glucose-6-phosphate dehydrogenase tests

Application

6-Phosphogluconic acid has been used in a study to assess the biochemistry of Coxiella burnetti. It has also been used in a study to investigate the enzymatic transfer of hydrogen.

Preparation Note

Prepared by a modification of the procedure of Seegmiller, J.E., et al., J. Biol. Chem., 192, 175 (1951).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H332

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCC5050
SLBZ8733
SLBP7427V
019K37851V
019K37851

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The enzymatic transfer of hydrogen. IX. The reactions catalyzed by glucose 6-phosphate dehydrogenase and 6-phosphogluconic dehydrogenase.
B K STERN et al.
The Journal of biological chemistry, 235, 205-208 (1960-01-01)
Divya Mathur et al.
Biochemical and biophysical research communications, 337(2), 626-632 (2005-10-11)
Phosphoglucose isomerase (PGI) is a well-characterized ubiquitous enzyme involved in the glycolytic pathway. It catalyzes the reversible isomerization of D-glucopyranose-6-phosphate and D-fructofuranose-6-phosphate and is present in all living cells. However, there is interspecies variation at the level of the primary
N Takahashi et al.
Journal of dental research, 89(12), 1383-1388 (2010-10-07)
Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway
Hulya Ayar-Kayali
Preparative biochemistry & biotechnology, 41(1), 94-105 (2011-01-14)
In vivo pentose phosphate pathway (PPP) enzymes such as glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH), and transaldolase (TAL) activities as well as ATP- and ADP-level variations of Amycolatopsis orientalis were investigated with respect to glucose concentration and incubation period. G6PDH
Scott Cameron et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 65(Pt 5), 450-454 (2009-05-02)
Two crystal structures of recombinant Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase (Gs6PDH) in complex with the substrate 6-phosphogluconate have been determined at medium resolution. Gs6PDH shares significant sequence identity and structural similarity with the enzymes from Lactococcus lactis, sheep liver and the
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