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P7627

Sigma-Aldrich

6-Phosphogluconic acid barium salt hydrate

Grade VI, ≥90%, powder

Synonym(s):

6-PG-Ba, D-Gluconate 6-phosphate barium salt

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About This Item

Empirical Formula (Hill Notation):
C6H10Ba1.5O10P · xH2O
CAS Number:
921-62-0
Molecular Weight:
479.10 (anhydrous basis)
Beilstein:
1729373
EC Number:
213-069-9
UNSPSC Code:
12352201
PubChem Substance ID:
24898864
NACRES:
NA.25

biological source

synthetic (organic)

type

Grade VI

Assay

≥90%

form

powder

color

white

storage temp.

−20°C

SMILES string

[O-]P(OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O)([O-])=O.[H]O[H].C

InChI

1S/C6H13O10P.CH4.H2O/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);1H4;1H2/p-3/t2-,3-,4+,5-;;/m1../s1

InChI key

VINGHIAQWNFZIR-ZBHRUSISSA-K

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General description

suitable for glucose-6-phosphate dehydrogenase tests

Application

6-Phosphogluconic acid has been used in a study to assess the biochemistry of Coxiella burnetti. It has also been used in a study to investigate the enzymatic transfer of hydrogen.

Preparation Note

Prepared by a modification of the procedure of Seegmiller, J.E., et al., J. Biol. Chem., 192, 175 (1951).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H332

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCC5050
SLBZ8733
SLBP7427V
019K37851V
019K37851

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Paolo A Calligari et al.
Proteins, 80(4), 1196-1210 (2012-01-26)
Nuclear magnetic resonance is used to investigate the backbone dynamics in 6-phosphogluconolactonase from Trypanosoma brucei (Tb6PGL) with (holo-) and without (apo-) 6-phosphogluconic acid as ligand. Relaxation data were analyzed using the model-free approach and reduced spectral density mapping. Comparison of
Hulya Ayar-Kayali
Preparative biochemistry & biotechnology, 41(1), 94-105 (2011-01-14)
In vivo pentose phosphate pathway (PPP) enzymes such as glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH), and transaldolase (TAL) activities as well as ATP- and ADP-level variations of Amycolatopsis orientalis were investigated with respect to glucose concentration and incubation period. G6PDH
Teresa del Castillo et al.
Journal of bacteriology, 189(14), 5142-5152 (2007-05-08)
In this study, we show that glucose catabolism in Pseudomonas putida occurs through the simultaneous operation of three pathways that converge at the level of 6-phosphogluconate, which is metabolized by the Edd and Eda Entner/Doudoroff enzymes to central metabolites. When
Hiroyoshi Matsumura et al.
Journal of molecular biology, 422(1), 75-86 (2012-05-23)
The key enzyme of plant photosynthesis, D-ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco), must be activated to become catalytically competent via the carbamylation of Lys201 of the large subunit and subsequent stabilization by Mg(2+) coordination. Many biochemical studies have reported that reduced nicotinamide
T L McDonald et al.
Journal of bacteriology, 102(1), 1-5 (1970-04-01)
Purified preparations of the rickettsial agent, Coxiella burnetii, have been examined for their ability to decarboxylate 6-phosphogluconate. The enzyme 6-phosphogluconic acid dehydrogenase [6-phospho-d-gluconate: NADP (nicotinamide adenine dinucleotide phosphate) oxidoreductase (decarboxylating), EC 1.1.1.44] was detected in extracts, but not in whole-cell
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