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P6888

Sigma-Aldrich

6-Phosphogluconic acid trisodium salt

≥95% anhydrous basis

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Synonym(s):
D-Gluconate 6-phosphate trisodium salt
Empirical Formula (Hill Notation):
C6H10Na3O10P
CAS Number:
53411-70-4
Molecular Weight:
342.08
Beilstein:
3814212
EC Number:
258-543-6
MDL number:
MFCD00083681
UNSPSC Code:
12352201
PubChem Substance ID:
24898802
NACRES:
NA.25

biological source

synthetic (inorganic)

Quality Level

200

Assay

≥95% anhydrous basis

form

powder

impurities

≤0.2% glucose-6-phosphate

color

light yellow

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 18-21% (anhydrous)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H13O10P.3Na/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);;;/q;3*+1/p-3/t2-,3-,4+,5-;;;/m1.../s1

InChI key

CBQSOSFCUWVWAQ-CXKLNRRHSA-K

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Application

6-Phosphogluconic acid has been used in a study to assess a new phosphorylated intermediate in glucose oxidation. It has also been used in a study to investigate direct oxidation of flucose-6-phosphate by animal tissues.

Preparation Note

Prepared enzymatically.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Direct oxidation of glucose-6-phosphate by animal tissues.
F DICKENS et al.
Nature, 166(4209), 33-33 (1950-07-01)
A new phosphorylated intermediate in glucose oxidation.
J MACGEE et al.
The Journal of biological chemistry, 210(2), 617-626 (1954-10-01)
Yasaman Barekatain et al.
Communications biology, 3(1), 328-328 (2020-06-27)
Magnetic resonance (MR) spectroscopy has potential to non-invasively detect metabolites of diagnostic significance for precision oncology. Yet, many metabolites have similar chemical shifts, yielding highly convoluted 1H spectra of intact biological material and limiting diagnostic utility. Here, we show that

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