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Merck
CN

P6210

Pyrantel pamoate

BioXtra

Synonym(s):

1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
UNSPSC Code:
51452307
NACRES:
NA.85
PubChem Substance ID:
24898655
EC Number:
244-837-1
Beilstein/REAXYS Number:
9034755
MDL number:
MFCD00072037

Key Documents

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cation traces

Ca: <0.002%, Al: <0.0005%, Cu: <0.0005%, Fe: <0.001%, K: <0.005%, Mg: <0.0005%, Na: <0.01%, Pb: <0.001%, Zn: <0.0005%

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

product line

BioXtra

form

powder

impurities

<0.0005% Phosphorus (P), <0.1% Insoluble matter

ign. residue

<0.5%

antibiotic activity spectrum

parasites

mode of action

enzyme | inhibits

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Application

It is a combination of pyrantel and pamoic acid. It is used to study mechanisms underlying gut dysfunction in a murine model.

Biochem/physiol Actions

Pyrantel pamoate is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SLBV0663
SLBR7047V
SLBN3363V
SLBL4475V
SLBJ9285V

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Kashinath Ghosh et al.
The Journal of infectious diseases, 193(1), 155-162 (2005-12-03)
The effect of concurrent (active) and treated hookworm infections on the immunogenicity of vaccination with the recombinant fusion protein Ay-Ancylostoma-secreted protein 2 was analyzed in the Golden Syrian hamster. Hamsters were infected with the hookworm Ancylostoma ceylanicum and vaccinated with
Vinod K Gupta et al.
Journal of colloid and interface science, 350(1), 330-335 (2010-07-21)
Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250
Education and imaging. Gastrointestinal: ascariasis.
A Suzuki et al.
Journal of gastroenterology and hepatology, 23(11), 1770-1770 (2009-01-06)
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A study was carried out to assess the field efficacy of moxidectin (MOX) against Parascaris equorum in foals. A total of 70 foals from 2 Italian thoroughbred (Farms 1 and 2) stud farms and one trotter stud farm (Farm 3)
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Journal of wildlife diseases, 51(3), 640-650 (2015-05-15)
Baylisascaris procyonis is a common gastrointestinal parasite of raccoons (Procyon lotor) and is a zoonotic helminth with the potential to cause severe or fatal infection. Raccoons thrive in human-dominated landscapes, and the fecal-oral transmission pathway and lack of effective treatment
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