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P6210

Sigma-Aldrich

Pyrantel pamoate

BioXtra

Synonym(s):

1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate

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About This Item

Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
Beilstein:
9034755
EC Number:
244-837-1
MDL number:
MFCD00072037
UNSPSC Code:
51101500
PubChem Substance ID:
24898655
NACRES:
NA.85

product line

BioXtra

form

powder

impurities

<0.0005% Phosphorus (P)
<0.1% Insoluble matter

ign. residue

<0.5%

cation traces

Al: <0.0005%
Ca: <0.002%
Cu: <0.0005%
Fe: <0.001%
K: <0.005%
Mg: <0.0005%
Na: <0.01%
Pb: <0.001%
Zn: <0.0005%

antibiotic activity spectrum

parasites

Mode of action

enzyme | inhibits

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

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Application

It is a combination of pyrantel and pamoic acid. It is used to study mechanisms underlying gut dysfunction in a murine model.

Biochem/physiol Actions

Pyrantel pamoate is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Baylisascaris procyonis is a common gastrointestinal parasite of raccoons (Procyon lotor) and is a zoonotic helminth with the potential to cause severe or fatal infection. Raccoons thrive in human-dominated landscapes, and the fecal-oral transmission pathway and lack of effective treatment
Vinod K Gupta et al.
Journal of colloid and interface science, 350(1), 330-335 (2010-07-21)
Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250
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