Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

P5874

Sigma-Aldrich

PTACH

≥98% (HPLC), solid

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Cpd 51, S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate
Empirical Formula (Hill Notation):
C20H26N2O2S2
CAS Number:
848354-66-5
Molecular Weight:
390.56
MDL number:
MFCD08705329
UNSPSC Code:
12352200
PubChem Substance ID:
24724582
NACRES:
NA.77

Assay

≥98% (HPLC)

form

solid

solubility

DMSO: 26 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c2ccccc2

InChI

1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)

InChI key

MDYDGUOQFUQOGE-UHFFFAOYSA-N

Biochem/physiol Actions

HDAC inhibitor; more potent than the majority of HDAC inhibitors except for SAHA (gold standard).

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Minghui Wang et al.
Neuron, 109(2), 257-272 (2020-11-26)
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors with varying cognitive and neuropathological phenotypes. Our analyses revealed thousands

Articles

Discover Bioactive Small Molecules for Gene Regulation

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service