P5669
Pyridoxine
≥98%
Synonym(s):
Pyridoxol, Vitamin B6
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About This Item
Empirical Formula (Hill Notation):
C8H11NO3
CAS Number:
Molecular Weight:
169.18
EC Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.28
Quality Level
Assay
≥98%
form
powder
technique(s)
HPLC: suitable
color
white to off-white
mp
159-162 °C (lit.)
SMILES string
Cc1ncc(CO)c(CO)c1O
InChI
1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
InChI key
LXNHXLLTXMVWPM-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
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General description
Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.
Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B6 is distributed in nuts, whole grains and animal meat.
Application
Pyridoxine has been used as a component of:
- artificial diet for sugarcane aphid pest
- modified Strullu and Romand (MSR) medium for carrot root organ culture
- Luria broth for E coli cultures
Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.
Biochem/physiol Actions
Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B6 leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Simultaneous high performance liquid chromatographic analysis of vitamins B1, B2 and B6 in royal jelly
Ana Elisa Presoto
Journal of the Brazilian Chemical Society, 15(1), 136-139 (2004)
Seizures caused by pyridoxine (vitamin B6) deficiency in adults: A case report and literature review
Tong Y
Intractable & rare diseases research, 3(2), 52-56 (2014)
E B Rimm et al.
JAMA, 279(5), 359-364 (1998-02-12)
Hyperhomocysteinemia is caused by genetic and lifestyle influences, including low intakes of folate and vitamin B6. However, prospective data relating intake of these vitamins to risk of coronary heart disease (CHD) are not available. To examine intakes of folate and
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