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P5648

Sigma-Aldrich

β-Propiolactone

Grade II, ≥90%

Synonym(s):

Oxetan-2-one, 3-Hydroxypropionic acid lactone, Hydracrylic acid β-lactone

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About This Item

Empirical Formula (Hill Notation):
C3H4O2
CAS Number:
57-57-8
Molecular Weight:
72.06
EC Number:
200-340-1
MDL number:
MFCD00005169
UNSPSC Code:
12352103
PubChem Substance ID:
24898684
NACRES:
NA.77

type

Grade II

Quality Level

200

Assay

≥90%

refractive index

n20/D 1.412 (lit.)

bp

162 °C (lit.)

mp

−33 °C (lit.)

density

1.146 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

O=C1CCO1

InChI

1S/C3H4O2/c4-3-1-2-5-3/h1-2H2

InChI key

VEZXCJBBBCKRPI-UHFFFAOYSA-N

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General description

β-Propiolactone is an alkylating agent which is mainly used in veterinary vaccines. It will not interfere with the antigenicity of vaccine.

Application

β-Propiolactone has been used for Influenza virus deactivation.

Caution

Insoluble polymers may form during storage.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H315,H319,H330,H350

Hazard Classifications

Acute Tox. 2 Inhalation - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

158.0 °F

Flash Point(C)

70 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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