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P5556

Sigma-Aldrich

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

Synonym(s):

Nonionic copolymer surfactant

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100 ML
¥283.21

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100 ML
¥283.21

About This Item

CAS Number:
9003-11-6
MDL number:
MFCD00082049
UNSPSC Code:
12161902
PubChem Substance ID:
24898666
NACRES:
NA.75

¥283.21

Available to ship on2025年4月10日Details

Request a Bulk Order

description

non-ionic

sterility

sterile-filtered

product line

BioReagent

mol wt

average mol wt 8350

concentration

10%

technique(s)

cell culture | insect: suitable

impurities

endotoxin, tested

transition temp

cloud point ≥100

HLB

29

SMILES string

O2C(C2)C.O1CC1

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This Item
K48941575916758
Sigma-Aldrich

P5556

Poloxamer 188 溶液

Kolliphor HS 188 solid

K4894

Kolliphor HS 188

Kolliphor P 188

15759

Kolliphor P 188

泊洛沙姆407 purified, non-ionic

16758

泊洛沙姆407

mol wt

average mol wt 8350

mol wt

8.400 g/mol

mol wt

~7680-9510 g/mol

mol wt

-

impurities

endotoxin, tested

impurities

-

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤1 ppm ethylene oxide, ≤1.0% water, ≤2 ppm arsenic traces, ≤20 ppm heavy metals, ≤5 ppm dioxan, ≤5 ppm propylene oxide, 50-150 ppm butylhydroxytoluene

impurities

≤1.0% water

CMC

0.04 mM

CMC

-

CMC

0.48 mM

CMC

-

description

non-ionic

description

-

description

-

description

-

Quality Level

400

Quality Level

200

Quality Level

200

Quality Level

100

General description

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]

Application

A nonionic copolymer surfactant

Biochem/physiol Actions

Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
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    Certificates of Analysis (COA)

    Lot/Batch Number
    RNBL8860
    RNBL4936
    RNBL1005
    RNBL0449
    RNBK5889

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