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Merck
CN

P5498

Anti-Pro-NGF antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Pro-Nerve Growth Factor

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About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
MFCD07370460

Key Documents

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Product Name

Anti-Pro-NGF antibody produced in rabbit, affinity isolated antibody, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat, human

technique(s)

immunohistochemistry: suitable
western blot: 1:200-1:500

UniProt accession no.

P08138

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... NGFR(4804)
mouse ... Ngfr(18053)
rat ... Ngfr(24596)

Related Categories

Biochem/physiol Actions

Does not cross react with pro-BDNF, pro-NT-3, or mature NGF.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

peptide corresponding to amino acid residues 84-104 of rat NGF (precursor). The sequence is identical in mouse and 16/21 residues identical in human.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA and <0.1% sodium azide

Preparation Note

Reconstitute the lyophilized vial with 0.2 ml deionized water.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H312,H412

Hazard Classifications

Acute Tox. 4 Dermal - Aquatic Chronic 3

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
SLCH9273
SLCF9500
SLBW8951
SLBV7581
SLBV4304

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Fan Zhang et al.
Molecular neurobiology, 58(9), 4237-4250 (2021-05-10)
Maternal subclinical hypothyroidism (SCH) during pregnancy can adversely affect the neurodevelopment of the offspring. The balance of nerve growth factor (NGF)-related tropomyosin receptor kinase A/p75 neurotrophin receptor (TrkA/p75NTR) signaling in the hippocampus is important in brain development, and whether it
Elahe Karimi et al.
Drug design, development and therapy, 13, 2513-2532 (2019-08-24)
Nowadays, the drug delivery system is important in the treatment of diseases. A polymeric nanoparticle modified by oleic acid (NPMO) as a Thymol (Thy) drug release system was synthesized from Thymbra spicata and its neurotrophic and angiogenic effects on rat's
Sabah Shiri et al.
RSC advances, 9(67), 38912-38927 (2019-11-27)
Drug delivery systems have been of interest to researchers. The effects of synthesized nano-polymers as silibinin and silymarin extract drug delivery systems on olfactory ensheathing cells under normal and high-glucose conditions were studied. The structure of the nanopolymer was characterized
Li Duan et al.
PloS one, 8(9), e73768-e73768 (2013-09-17)
While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer's and Parkinson's disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotrophins. By in
Yi Xia et al.
International journal of molecular sciences, 14(7), 14085-14104 (2013-07-25)
Growing evidence has shown that proNGF-p75NTR-sortilin signaling might be a crucial factor in neurodegeneration, but it remains unclear if it may function in nigral neurons under aging and disease. The purpose of this study is to examine and quantify proNGF

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