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Key Documents

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Safety Information

P4630

Sigma-Aldrich

Protease from bovine pancreas

Type I, ≥5 units/mg solid

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About This Item

CAS Number:
9001-92-7
EC Number:
232-642-4
MDL number:
MFCD00132092
UNSPSC Code:
12352204
eCl@ss:
32160410
NACRES:
NA.54
To inquire about this product P4630, please contact your local Merck office or dealer. Contact Technical Service

biological source

bovine pancreas

Quality Level

200

type

Type I

form

powder

specific activity

≥5 units/mg solid

storage temp.

−20°C

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technique(s)

cell culture | hybridoma: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in HEK 293 cells

biological source

human

biological source

human

biological source

human

biological source

human

assay

>98% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥97% (HPLC and SDS-PAGE)

assay

≥98% (SDS-PAGE)

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

200

form

solution

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Application

Non-specific Protease Activity Assay Video
Protease is an enzyme used to break down proteins by hydrolyzing peptide bonds. Protease is used to degrade proteins, to study protease inhibitors and to study thermal inactivation kinetics. Product P4630 is from bovine pancreas. Protease from bovine pancrease (type I) has been used for the extraction of hemicellulose[1].

Biochem/physiol Actions

Protease catabolizes proteins by hydrolysis of peptide bonds. Proteases are inactivated by serine active-site inhibitors, such as phenylmethylsulfonyl fluoride (PMSF) and diisopropylfluorophosphate.

Quality

Crude

Unit Definition

One unit will hydrolyze casein to produce color equivalent to 1.0 μmole (181 μg) of tyrosine per min at pH 7.5 at 37 °C (color by Folin-Ciocalteu reagent), unless otherwise indicated.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H334,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

动植物源性产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000416145
    0000416145
    0000398963
    0000398964
    0000353518

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