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Merck
CN

P3531

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine

≥99%

Synonym(s):

1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, 1,2-distearoyl, L-β,γ-Distearoyl-α-cephalin

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About This Item

Empirical Formula (Hill Notation):
C41H82NO8P
CAS Number:
Molecular Weight:
748.07
UNSPSC Code:
12352207
NACRES:
NA.77
PubChem Substance ID:
EC Number:
213-963-9
Beilstein/REAXYS Number:
1730641
MDL number:
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InChI key

LVNGJLRDBYCPGB-LDLOPFEMSA-N

InChI

1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC

assay

≥99%

form

powder

lipid type

phospholipids

storage temp.

−20°C

Quality Level

Application


  • Injectable Composite Hydrogels Embedded with Gallium-Based Liquid Metal Particles for Solid Breast Cancer Treatment via Chemo-Photothermal Combination.: This article presents the use of DSPE in developing injectable composite hydrogels. These hydrogels are embedded with liquid metal particles to provide a dual-mode treatment approach combining chemotherapy and photothermal therapy for breast cancer (Lee et al., 2024).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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ACS nano, 12(8), 7583-7600 (2018-07-14)
Nanomedicine drug delivery systems are capable of transporting significant payloads to solid tumors. However, only a modest increase in antitumor efficacy relative to the standard of care has been observed. In this study, we demonstrate that a single dose of
Ching-Hsiang Fan et al.
ACS synthetic biology, 6(11), 2021-2027 (2017-09-26)
We developed an ultrasound-chemical hybrid tool to precisely manipulate cellular activities. A focused ultrasound coupled with gas-filled microbubbles was used to rapidly trigger the influx of membrane-impermeable chemical dimerizers into living cells to regulate protein dimerization and location without inducing
Eirik Hagtvet et al.
Journal of drug targeting, 19(8), 701-708 (2011-04-29)
Liposomal encapsulation of doxorubicin (DXR) improves tumor accumulation and reduces adverse effects. One possible strategy for further optimization of this delivery technology would be to design the liposome carrier to release its content within the tumor tissue in response to
Sandro Sieber et al.
Nanomedicine : nanotechnology, biology, and medicine, 17, 82-93 (2019-01-20)
Macrophage recognition of nanoparticles is highly influenced by particle size and surface modification. Due to the lack of appropriate in vivo screening models, it is still challenging and time-consuming to characterize and optimize nanomedicines regarding this undesired clearance mechanism. Therefore

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