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P3440

Sigma-Aldrich

Polyoxyethylene (40) stearate

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Synonym(s):
Myrj 52
CAS Number:
MDL number:
UNSPSC Code:
12161900
NACRES:
NA.25

description

non-ionic

Quality Level

form

powder

application(s)

detection

InChI

1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3

InChI key

RFVNOJDQRGSOEL-UHFFFAOYSA-N

General description

Polyoxyethylene (40) stearate is a neutral surfactant.

Application

Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. It has also been used in a study to investigate its effects on multidrug resistance (MDR).

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450.
Zhu, S., et al.
European Journal of Pharmaceutical Sciences, 37, 8-8 (2009)
Lingying Luo et al.
The AAPS journal, 9(3), E329-E335 (2008-01-04)
Multidrug resistance (MDR) is one of the major obstacles limiting the efficacy of cancer chemotherapy. Identification of new and effective MDR reversal agents is needed. In this study, the effects of polyoxyethylene 40 stearate (PS40) on MDR were evaluated via
Alexandra Kosareva et al.
Ultrasound in medicine & biology, 47(9), 2664-2675 (2021-06-20)
Clinical translation of ultrasound molecular imaging will depend on the development of binders that can easily be generated, manufactured and coupled, and that are compatible with in vivo use. We describe targeted microbubbles (MBs) using designed ankyrin repeat proteins (DARPins)
Michalakis Savva et al.
Colloids and surfaces. A, Physicochemical and engineering aspects, 325(1-2), 1-6 (2009-07-18)
The feasibility of a method based on mass preservation [G. Schwarz, J. Zhang, Chem. Phys. Lipids, 110 (2001) 35-45] to determine the solubility of Cholesterol in water from monomolecular films on air/water interface was investigated. Using a mass balance equation
Adam J Shuhendler et al.
Journal of controlled release : official journal of the Controlled Release Society, 157(3), 478-484 (2011-09-24)
For effective and safe thermotherapy, real-time, accurate, three-dimensional tissue thermometry is required. Magnetic resonance imaging (MRI)-based thermometry in combination with current temperature responsive contrast agents only provides an 'off-on' signal at a certain temperature, not indicating temperature increases beyond the

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