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P2663

Sigma-Aldrich

1,2-Dimyristoyl-sn-glycero-3-phosphocholine

≥99%

Synonym(s):

1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dimyristoyl, L-β,γ-Dimyristoyl-α-lecithin

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About This Item

Empirical Formula (Hill Notation):
C36H72NO8P
CAS Number:
18194-24-6
Molecular Weight:
677.93
Beilstein:
3921768
EC Number:
242-085-9
MDL number:
MFCD00036901
UNSPSC Code:
12352211
PubChem Substance ID:
24898347
NACRES:
NA.77

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Assay

≥99%

form

powder

lipid type

phosphoglycerides

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O

InChI

1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1

InChI key

CITHEXJVPOWHKC-UUWRZZSWSA-N

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1,2-二油酰- 锡 -甘油基-3-磷酸胆碱 lyophilized powder

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1,2-二油酰- 锡 -甘油基-3-磷酸胆碱

L-α-磷脂酰胆碱 egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder

P3556

L-α-磷脂酰胆碱

L-α-磷脂酰胆碱 from soybean, Type III-S, ≥99% (TLC), 50-150 mg/mL in chloroform, solution

P6263

L-α-磷脂酰胆碱

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

lyophilized powder

form

lyophilized powder

form

solution

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

lipid type

phosphoglycerides

lipid type

phosphoglycerides

lipid type

phosphoglycerides

lipid type

-

Application

1,2-Dimyristoyl-sn-glycero-3-phosphocholine has been used as a standard for phospholipid analysis by LC-ESI-MS.[1]

Biochem/physiol Actions

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) has the ability to enhance the constancy and in vitro antiproliferative effect of carmofur.[2]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000320143
    0000369834
    0000310174
    0000320142
    0000320131

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    1, 2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) increases Carmofur stability and in vitro antiproliferative effect
    Domracheva I, et al.
    Toxicology Reports, 2, 377-383 (2015)
    Assessment of the effects of hydrocarbon contamination on the sedimentary bacterial communities and determination of the polar lipid fraction purity: relevance of intact phospholipid analysis
    Mazzella N, et al.
    Marine Chemistry, 103(3-4), 304-317 (2007)
    Brian S Vad et al.
    The Journal of membrane biology, 248(3), 487-496 (2015-03-25)
    The biological activity of antimicrobial peptides is believed to be closely linked to their ability to perturb bacterial membranes. This makes it important to understand the basis of their membrane-binding properties. Here, we present a biophysical analysis of the interactions
    Sevim Ozgur et al.
    Molecular and cellular biology, 30(17), 4308-4323 (2010-06-30)
    In eukaryotic cells, degradation of many mRNAs is initiated by removal of the poly(A) tail followed by decapping and 5'-3' exonucleolytic decay. Although the order of these events is well established, we are still lacking a mechanistic understanding of how
    Haiming Luo et al.
    ACS nano, 8(5), 4334-4347 (2014-04-29)
    Current treatment of advanced-stage nasopharyngeal carcinoma (NPC) is not satisfactory. Targeted therapies offer hope for extending survival. Here, we developed simple, robust, and NPC-specific therapeutic lipid nanoparticles based on a fusion peptide, α-NTP, made up of an amphipathic α-helical peptide
    View All Related Papers

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