P2124
Anti-phospho-Polo-Like Kinase Kinase (pSer482, pSer486, pSer490) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
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Synonym(s):
Anti-phospho-PLKK
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen ~120 kDa
species reactivity
Xenopus
technique(s)
western blot: 1:1,000 using Xenopus lysates
shipped in
wet ice
storage temp.
−20°C
Gene Information
Xenopus laevis ... stk10-a(373731)
General description
Polo-Like Kinase Kinase (PLKK) is a 120kD protein that belongs to the serine/threonine kinase family. It has a crucial role in regulating cellular events in cytokinesis and mitosis. Anti-phospho-polo-like kinase kinase (pSer482, pSer486, pSer490) antibody can be used in immunoblotting (diluted 1:1000). Rabbit anti- phospho-polo-like kinase kinase antibody reacts specifically with phospho-polo-like kinase kinase of xenopus.
Immunogen
synthetic phosphopeptide corresponding to amino acids residues surrounding the Xenopus polo-like kinase kinase phosphorylated on serines 482, 486 and 490.
Application
Anti-phospho-polo-like kinase kinase (pSer482, pSer486, pSer490) antibody can be used in western blotting (diluted 1:1000).
Physical form
Solution in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.
related product
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Y W Qian et al.
Science (New York, N.Y.), 282(5394), 1701-1704 (1998-11-30)
The Xenopus polo-like kinase 1 (Plx1) is essential during mitosis for the activation of Cdc25C, for spindle assembly, and for cyclin B degradation. Polo-like kinases from various organisms are activated by phosphorylation by an unidentified protein kinase. A protein kinase
Xingjie Ma et al.
Aging cell, 17(6), e12831-e12831 (2018-09-15)
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