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P1691

Sigma-Aldrich

Poly(D,L-lactide)

mol wt 75,000-120,000

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Synonym(s):
Poly[oxy(1-methyl-2-oxo-1,2-ethanediyl)]
Linear Formula:
(C3H4O2)n
CAS Number:
26023-30-3
MDL number:
MFCD00131929
UNSPSC Code:
12352209
PubChem Substance ID:
24898237
NACRES:
NA.26

form

pellets

Quality Level

100

mol wt

75,000-120,000

color

white to yellow

mp

262 °C (lit.)

transition temp

Tg 32.9 °C

storage temp.

−20°C

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Biochem/physiol Actions

Poly(D,L-lactide) is a polyamino acid that has been used to as a coating material.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Local application of zoledronic acid incorporated in a poly (D, L-lactide)-coated implant accelerates fracture healing in rats
Greiner, S.H. et al.
Acta Orthopaedica, 29, 717-725 (2008)
Ayelen L Helling et al.
Tissue engineering. Part A, 25(3-4), 214-223 (2018-10-04)
In human skin the junction between the epidermis and dermis undulates. Epidermal stem cells pattern according to their position relative to those undulations. Here we describe a rig in which epidermal cells are cultured on a collagen-coated poly(d,l-lactide-co-glycolide) (PLGA) membrane.

Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

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