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Safety Information

P1476

Sigma-Aldrich

Pituitary Extract bovine

solution, ~14 mg/mL protein in PBS, 0.2 μm filtered

Synonym(s):

BPE, PEX

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About This Item

MDL number:
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

bovine

sterility

0.2 μm filtered

form

solution

quality

endotoxin tested

packaging

pkg of 2.5 and 25 mL

concentration

~14 mg/mL protein in PBS

impurities

<50 EU/mL

color

brown

storage temp.

−20°C

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General description

Pituitary Extract, bovine (PEX) is an extract of bovine pituitary tissue containing growth factors. PEX can be used to promote the growth of several types of human epithelial cells in culture. Pituitary extract, bovine, is prepared using a modification of a published procedure.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Jie Liu et al.
Animal reproduction science, 115(1-4), 49-57 (2008-12-26)
Different culture systems were evaluated for their ability to support attachment and proliferation of the somatic cells obtained from ovine semen. Ejaculates (n=14) were collected from eight rams representing three breeds, Dorper, Suffolk and Hampshire. All samples were processed immediately
J C Willey et al.
Journal of cellular physiology, 124(2), 207-212 (1985-08-01)
The mechanisms of action of extracellular mitogens for normal human bronchial epithelial cells (NHBE) were investigated by observing their effects on selected biochemical pathways when the cells were incubated in serum-free media. We find that (a) epidermal growth factor (EGF)
S L Hammond et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(17), 5435-5439 (1984-09-01)
A serum-free medium with bovine pituitary extract as the only undefined supplement has been developed for long-term culture of human mammary epithelial cells. This medium supports serial subculture of normal cells for 10-20 passages (1:10 splits) without conditioning or special
Yan Hu et al.
Stem cells (Dayton, Ohio), 38(11), 1467-1478 (2020-06-12)
Wnt/β-catenin signaling regulates progenitor cell fate decisions during lung development and in various adult tissues. Ectopic activation of Wnt/β-catenin signaling promotes tissue repair in emphysema, a devastating lung disease with progressive loss of parenchymal lung tissue. The identity of Wnt/β-catenin
Li Na Zhou et al.
Stem cell research & therapy, 11(1), 153-153 (2020-04-11)
To date, it has repeatedly been demonstrated that infusing bone marrow-derived stem cells (BMSCs) into acellular nerve scaffolds can promote and support axon regeneration through a peripheral nerve defect. However, harvesting BMSCs is an invasive and painful process fraught with

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