P1178
Phloroglucinol
BioReagent, suitable for plant cell culture
Synonym(s):
1,3,5-Trihydroxybenzene
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About This Item
Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
Beilstein:
1341907
EC Number:
MDL number:
UNSPSC Code:
10171502
PubChem Substance ID:
NACRES:
NA.72
product line
BioReagent
Quality Level
form
powder
technique(s)
cell culture | plant: suitable
application(s)
agriculture
SMILES string
Oc1cc(O)cc(O)c1
InChI
1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
InChI key
QCDYQQDYXPDABM-UHFFFAOYSA-N
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General description
Phloroglucinol is a trihydroxybenzene with antithrombotic, profibrinolytic, antimicrobial, antimalarial, cancer chemopreventive, anti-HIV and anti-leishmanial activities. Phloroglucinol (PG) is a biosynthetic precursor of the 2,4-diacetylphloroglucinol (DAPG) an antibiotic against soil-borne diseases. Phloroglucinol is a useful intermediate because it is polyfunctional.
Application
Phloroglucinol has been used to prevent hyperhydricity by promoting lignification of shoots. It has also been used in PG (phloroglucinol)-sucrose treatments for growth and development of in vitro derived shoot tips.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
危险化学品
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Phloroglucinol enhances growth and rate of axillary shoot proliferation in potato shoot tip cultures in vitro
Sarkar D and Naik P S
Plant Cell, Tissue and Organ Culture, 60(2), 139-149 (2000)
In vitro propagation of `Guayabo del pais?(Acca sellowiana (Berg.) Burret)
Ross S and Grasso R
Fruit, Vegetable and Cereal Science and Biotechnology, 4(1), 83-87 (2010)
Jong-Sup Bae
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 49(7), 1572-1577 (2011-04-20)
Phloroglucinol is the monomeric units of phlorotannins abundant in brown algae. Several biological effects of phloroglucinol have been reported, however, antithrombotic and profibrinolytic activities of phloroglucinol have not been studied yet. In this study, the anticoagulant properties of phloroglucinol were
Yong Li et al.
Bioorganic & medicinal chemistry, 17(5), 1963-1973 (2009-02-10)
Seven phlorotannins were isolated and characterized from an edible marine brown alga Ecklonia cava (EC), along with three common sterol derivatives (fucosterol, ergosterol, and cholesterol) according to the comprehensive spectral analysis of MS and NMR data. Compounds 5 (7-phloro eckol)
Liva Harinantenaina et al.
Journal of natural products, 76(3), 388-393 (2013-01-05)
Bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of Mallotus oppositifolius collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotojaponins B (1) and C (2), together with the known mallotophenone (3).
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