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Merck
CN

P0747

8-MA-cAMP

≥98% (HPLC), solid

Synonym(s):

8-Methylaminoadenosine-3′,5′-cyclic monophosphate sodium salt

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About This Item

Empirical Formula (Hill Notation):
C11H14N6O6PNa
CAS Number:
33823-18-6
Molecular Weight:
380.23
UNSPSC Code:
12352200
PubChem Substance ID:
24724571
MDL number:
MFCD04113731

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InChI

1S/C11H15N6O6P.Na/c1-13-11-16-5-8(12)14-3-15-9(5)17(11)10-6(18)7-4(22-10)2-21-24(19,20)23-7;/h3-4,6-7,10,18H,2H2,1H3,(H,13,16)(H,19,20)(H2,12,14,15);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1

SMILES string

[Na+].CNc1nc2c(N)ncnc2n1[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O

InChI key

PYXGPPLPPUIPRE-MCDZGGTQSA-M

assay

≥98% (HPLC)

form

solid

packaging

pkg of 10 μmol

color

white

solubility

H2O: freely soluble

shipped in

dry ice

storage temp.

−70°C

Biochem/physiol Actions

Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
064K4729

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