Skip to Content
Merck
CN
All Photos(3)

Documents

Safety Information

P0689

Sigma-Aldrich

(R)-(+)-Propranolol hydrochloride

≥98% (TLC)

Sign Into View Organizational & Contract Pricing
All Photos(3)
Synonym(s):
Propranolol HCl, (R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
Linear Formula:
C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl
CAS Number:
13071-11-9
Molecular Weight:
295.80
Beilstein:
5780490
EC Number:
235-961-7
MDL number:
MFCD00064546
UNSPSC Code:
12352200
PubChem Substance ID:
24898124
NACRES:
NA.77

Quality Level

200

Assay

≥98% (TLC)

mp

196-198 °C (lit.)

solubility

ethanol: 10 mg/mL
DMSO: <14.5 mg/mL
H2O: 50 mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL

originator

AstraZeneca

storage temp.

2-8°C

SMILES string

Cl.CC(C)NC[C@@H](O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1

InChI key

ZMRUPTIKESYGQW-PFEQFJNWSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Less active enantiomer of propranolol.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Montserrat Solé et al.
Analytical and bioanalytical chemistry, 396(2), 649-656 (2009-10-20)
Environmental risk assessments of human pharmaceuticals and other 'emerging contaminants' should integrate both population-relevant endpoints and biomarkers of potential modes of action in a range of species. Adult Mytilus galloprovincialis were exposed to the beta-adrenergic receptor blocker propranolol or to
Silvia Gramolelli et al.
Cancer research, 80(15), 3116-3129 (2020-06-11)
Kaposi sarcoma is a tumor caused by Kaposi sarcoma herpesvirus (KSHV) infection and is thought to originate from lymphatic endothelial cells (LEC). While KSHV establishes latency in virtually all susceptible cell types, LECs support spontaneous expression of oncogenic lytic genes
Jieyu Xu et al.
Toxicology in vitro : an international journal published in association with BIBRA, 48, 286-301 (2018-02-07)
Immortalized liver cells have been used for evaluating the toxicity of compounds; however, excessive glutathione is considered to lessen cytotoxicity. In this study, we compared the effects of glutathione depletion on cytotoxicities of drugs using HepaRG and HepG2 cells, which

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service