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Merck
CN

P0109

Phytic acid sodium salt hydrate

from rice, ≥90% phosphorus (P) basis

Synonym(s):

myo-Inositol hexakis(dihydrogen phosphate), Inositol hexakisphosphate, Inositol hexaphosphoric acid, InsP6

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About This Item

Empirical Formula (Hill Notation):
C6H18O24P6 · xNa+ · yH2O
CAS Number:
14306-25-3
Molecular Weight:
660.04 (anhydrous free acid basis)
UNSPSC Code:
12352201
EC Number:
238-242-6

Key Documents

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Product Name

Phytic acid sodium salt hydrate, from rice, ≥90% phosphorus (P) basis

InChI key

KETSPIPODMGOEJ-UHFFFAOYSA-B

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O

InChI

1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12

biological source

rice

assay

≥90% phosphorus (P) basis

composition

Sodium, ≥10 mol/mol ICP

impurities

≤0.1% Inorganic phosphorus

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Application

Recommended for use as phytase substrate due to low inorganic phosphorus content. Phytic acid has been used as an anti-nutrient factor in a study to assess the effect of processing on the African locust bean. It has also been used in a study to investigate the effect of dietary rice bran component γ-oryzanol on tumor growth.

Biochem/physiol Actions

Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).

General description

Phytic acid is a major determinant of zinc bioavailability.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBH8701
BCBD7269V
BCBD7269
BCBD0209
BCBM7263

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Stéphanie Devineau et al.
Langmuir : the ACS journal of surfaces and colloids, 33(13), 3241-3252 (2017-03-07)
The connection between the mechanisms of protein adsorption on nanoparticles and the structural and functional properties of the adsorbed protein often remains unclear. We investigate porcine hemoglobin adsorption on silica nanoparticles, and we analyze the structural and functional modifications of
Ameny Farhat-Khemakhem et al.
AMB Express, 2(1), 10-10 (2012-01-28)
To attempt cost-effective production of US417 phytase in Bacillus subtilis, we developed an efficient system for its large-scale production in the generally recognized as safe microorganism B. subtilis 168. Hence, the phy US417 corresponding gene was cloned in the pMSP3535
Fei Dai et al.
PloS one, 6(4), e18829-e18829 (2011-05-03)
Endogenous phytase plays a crucial role in phytate degradation and is thus closely related to nutrient efficiency in barley products. The understanding of genetic information of phytase in barley can provide a useful tool for breeding new barley varieties with
L de P Naves et al.
Asian-Australasian journal of animal sciences, 27(7), 1003-1012 (2014-07-23)
The use of a suitable methodology to quantify the phytate phosphorus (Pphy) content in both the feed and the excreta from broilers is required to enable accurate calculation of the catalytic efficiency of the phytase supplemented in the feed. This
Zizhong Tang et al.
Enzyme and microbial technology, 108, 74-81 (2017-11-08)
We previously constructed three recombinant phyA mutant strains (PP-NP
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