O7889
Anti-OMP antibody produced in rabbit
~2 mg/mL, affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Olfactory Marker Protein
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~19 kDa
species reactivity
rat, mouse
concentration
~2 mg/mL
technique(s)
western blot: 0.5-1.0 μg/mL using rat brain (olfactory bulb) extract (S1 fraction).
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Omp(24612)
General description
Olfactory marker protein (OMP) is a phylogenetically conserved cytoplasmic protein of unknown function expressed almost exclusively in mature olfactory sensory neurons, in essentially all vertebrate species. OMP is expressed in both the olfactory neuroepithelium and the olfactory nerve projection to the olfactory bulb. In perikaryon, OMP is produced and are transported to the dendrite and axon in the glomerular layer of the olfactory bulb.
Olfactory marker protein (OMP) is a phylogenetically conserved, 19kDa, cytoplasmic protein of unknown function expressed almost exclusively in mature olfactory sensory neurons, in essentially all vertebrate species. The gene encoding OMP is localized on rat chromosome 1. OMP expression is initially detected in rat and mouse embryo during the last trimester of gestation and reaches adult levels at 2-4 weeks postnatally. It has been suggested that OMP is a novel modulatory component of the odor detection signal transduction cascade that is developmentally and physiologically regulated.
Immunogen
synthetic peptide corresponding to amino acids 119-137 located near the C-terminus of rat OMP conjugated to KLH.
Application
Anti-OMP antibody produced in rabbit has been used in immunohistochemistry.
Anti-OMP antibody produced in rabbit has been used in:
- immunoblotting
- double immunofluorescence
- staining
Biochem/physiol Actions
Olfactory marker protein (OMP) helps to modulate the formation and refinement of the olfactory glomerular map. OMP-deficient mice generated by gene targeting in embryonic stem (ES) cells are compromised in their ability to respond to odor stimuli. In the OMP-null mouse, in addition to reduced odorant response, the levels of neural tyrosine hydroxylase (TH) and neuropeptide cholecystokinin (CCK) are severely reduced. It has been suggested that OMP is a novel modulatory component of the odor detection signal transduction cascade that is developmentally and physiologically regulated.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Cytotoxic effect of 5-bromo-2-deoxyuridine on olfactory epithelium
Raices M, et al.
MOJ proteomics & bioinformatics, 10-15406 (2015)
Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
Albeanu DF, et al.
Nature Communications, 5073-5073 (2018)
Olfactory bulb increases marker protein in olfactory receptor cells
Chuah MI, et al.
The Journal of Neuroscience, 3(11), 2197-2205 (1983)
Yun-Feng Zhang et al.
iScience, 25(5), 104284-104284 (2022-05-20)
Self-grooming is a stereotyped behavior displayed by nearly all animals. Among other established functions, self-grooming is implicated in social communication. However, whether self-grooming specifically influences behaviors of nearby individuals has not been directly tested, partly because of the technical challenge
Backbone dynamics of the olfactory marker protein as studied by 15N NMR relaxation measurements.
Biochemistry, 44(28), 9673-9679 (2005)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service