O7139
Monoclonal Anti-Oligodendrocyte Marker O4 antibody produced in mouse
clone O4, purified immunoglobulin, lyophilized powder
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biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
O4, monoclonal
form
lyophilized powder
species reactivity
mouse, rat, chicken, human
technique(s)
flow cytometry: 0.25 μg/106 cells (Rat differentiated cortical stem cells)
immunocytochemistry: 1-10 μg/mL
isotype
IgM
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... OMG(4974)
Related Categories
General description
Monoclonal anti-oligodendrocyte marker O4 was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with white matter of the corpus callosum from bovine brain. Oligodendrocytes are myelinating cells in the central nervous system (CNS) that form the myelin sheath of axons to support rapid nerve conduction.
Immunogen
white matter of corpus callosum from bovine brain.
Application
Monoclonal anti-oligodendrocyte marker O4 antibody produced in mouse has been used in immunocytochemistry and immunofluorescence.
Biochem/physiol Actions
Oligodendrocyte marker O4 functions as a development marker of oligodendrocytes. The monoclonal anti-oligodendrocyte marker O4 antibody has been used to describe a biologically distinct stage of the oligodendroglial lineage in-vitro.†
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
related product
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Certificates of Analysis (COA)
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Oligodendrocytes: biology and pathology
Bradl M, et al.
Acta Neuropathologica, 119, 37-53 (2010)
Neuroglial Cells in Long-Term Primary Cultures from the Gilthead Seabream (Sparus Aurata L.): New Functional In Vitro Model from Bony Fish Brain
Centoducati G, et al.
Italian Journal of Animal Science, 12 (2013)
An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells.
Niu J, et al.
Journal of Neuroscience Methods, 209, 241-249 (2012)
Shuhui Yang et al.
ACS omega, 4(19), 18136-18146 (2019-11-14)
Neural stem cells (NSCs) play an important role in neural tissue engineering because of their capacity of self-renewal and differentiation to multiple cell lineages. The in vitro conventional neurosphere culture protocol has some limitations such as limited nutrition and oxygen
Xiao-Long Guo et al.
Communications biology, 2, 59-59 (2019-02-19)
Bacterial pore-forming toxin aerolysin-like proteins (ALPs) are widely distributed in animals and plants. However, functional studies on these ALPs remain in their infancy. βγ-CAT is the first example of a secreted pore-forming protein that functions to modulate the endolysosome pathway
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