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Safety Information

N9164

Sigma-Aldrich

nanoHA5

low endotoxin

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UNSPSC Code:
12352201

form

solid

quality

low endotoxin

impurities

≤1 EU/mg endotoxin

storage temp.

−20°C

General description

The nanoHA products are small-molecular weight hyaluronic acid oligomers prepared by chemoenzymatic synthesis using immobilized enzymes. The name of each nanoHA indicates the number of monosaccharide units in the oligomer. The reducing end contains N-acetyl-D-glucosamine.

Application

NanoHA has been used in a study to assess the development of nano-sized hydroxyapatite reinforced composites for tissue engineering scaffolds. It has also been used in a study to investigate the use of electrospun bioactive nanocomposite scaffolds for bone tissue engineering.

Other Notes

nanoHA5 is a pentasaccharide containing two hyaluronan disaccharide subunits (GlcNAcβ4GlcAβ3GlcNAcβ4GlcAβ3GlcNAcβ4).
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Physical form

Supplied lyophilized as the ammonium and/or sodium salt.

Analysis Note

Sold on the basis of carbohydrate as determined by carbazole assay.

Legal Information

nanoHA is a trademark of Hyalose LLC

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vinoy Thomas et al.
Biomacromolecules, 8(2), 631-637 (2007-01-30)
Nanofibrous biocomposite scaffolds of type I collagen and nanohydroxyapatite (nanoHA) of varying compositions (wt %) were prepared by electrostatic cospinning. The scaffolds were characterized for structure and morphology by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), atomic force
Jie Huang et al.
Journal of materials science. Materials in medicine, 18(11), 2151-2157 (2007-09-25)
Nano-sized hydroxyapatite (nanoHA) reinforced composites, mimicking natural bone, were produced. Examination by transmission electron microscopy revealed that the nanoHA particles had a rod-like morphology, 20-30 nm in width and 50-80 nm in length. The phase composition of hydroxyapatite was confirmed
Vinoy Thomas et al.
Journal of nanoscience and nanotechnology, 6(2), 487-493 (2006-04-01)
Nanocomposite scaffolds based on nanofibrous poly(epsilon-caprolactone) (PCL) and nanohydroxyapatite (nanoHA) with different compositions (wt%) were prepared by electrostatic co-spinning to mimic the nano-features of the natural extracellular matrix (ECM). NanoHA was found to be well dispersed in polymers up to

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