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Safety Information

N9039

Sigma-Aldrich

nanoHA™7

low endotoxin

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UNSPSC Code:
12352201

form

film

quality

low endotoxin

impurities

≤1 EU/mg endotoxin

storage temp.

−20°C

General description

The nanoHA products are small-molecular weight hyaluronic acid oligomers prepared by chemoenzymatic synthesis using immobilized enzymes. The name of each nanoHA indicates the number of monosaccharide units in the oligomer. The reducing end contains N-acetyl-D-glucosamine.

Application

NanoHA has been used in a study to assess the nanomechanical properties of electrospun composite scaffolds. It has also been used in a study to investigate the influence of crystallite size of nanophased hydroxyapatite on fibronectin and osteonectin adsorption and on osteoblast adhesion and morphology.

Other Notes

nanoHA7 is a heptasaccharide containing three hyaluronan disaccharide subunits (GlcNAcβ4GlcAβ3GlcNAcβ4GlcAβ3GlcNAcβ4GlcAβ3GlcNAcβ4).
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Physical form

Supplied lyophilized as the ammonium and/or sodium salt.

Analysis Note

Sold on the basis of carbohydrate as determined by carbazole assay.

Legal Information

nanoHA is a trademark of Hyalose LLC

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molecular weight for Product N9039, nanoHA?

    For product N9039 nanoHA, we have calculated a molecular weight of 1359.2 g/mole, based on the molecular formula C50H78N4O39.

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    Ask a Scientist here.

Parul Tyagi et al.
Journal of nanoscience and nanotechnology, 9(8), 4839-4845 (2009-11-26)
Fibrous nanocomposite scaffolds were electrospun from dispersions of hydroxyapatite nanoparticles (nanoHA) in polycaprolactone (PCL) with varying nanoHA contents (from 0% to 50% by weight). Such scaffolds were produced to mimic the nano-features of the extracellular matrix (ECM) for natural bone
N Ribeiro et al.
Journal of colloid and interface science, 351(2), 398-406 (2010-09-03)
The characteristic topographical features (crystallite dimensions, surface morphology and roughness) of bioceramics may influence the adsorption of proteins relevant to bone regeneration. This work aims at analyzing the influence of two distinct nanophased hydroxyapatite (HA) ceramics, HA725 and HA1000 on
Staphylococcus aureus and Staphylococcus epidermidis adhesion to nanohydroxyapatite in the presence of model proteins
Ribeiro, M., et al.
Bio-medical materials and engineering, 7, 045010-045010 (2012)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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