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Merck
CN

N8000

1-Naphthyl butyrate

esterase substrate, ≥99% (GC), liquid

Synonym(s):

Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester

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About This Item

Linear Formula:
CH3CH2CH2CO2C10H7
CAS Number:
3121-70-8
Molecular Weight:
214.26
NACRES:
NA.32
PubChem Substance ID:
24897845
UNSPSC Code:
12352204
EC Number:
221-500-7
MDL number:
MFCD00003923
Beilstein/REAXYS Number:
2558646

Key Documents

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Product Name

1-Naphthyl butyrate,

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

InChI key

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

SMILES string

CCCC(=O)Oc1cccc2ccccc12

Quality Level

200

assay

≥99% (GC)

form

liquid

bp

125-130 °C/1 mmHg (lit.)

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

density

1.091 g/mL at 20 °C (lit.)

storage temp.

−20°C

General description

Esterase substrate.

Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Biochem/physiol Actions

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM6290
0000430007
0000430007
0000225467
0000225467

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P M Mattes et al.
Toxicology and applied pharmacology, 114(1), 71-76 (1992-05-01)
Carboxylesterase activity in the rat nasal mucosa plays an important role in the response of this tissue to certain toxic inhaled esters. We have examined this activity in extracts of both Fischer-344 rat and human nasal tissue using the substrate
J Yourno et al.
Blood, 60(1), 24-29 (1982-07-01)
Lymphocytes from a case of B-cell chronic lymphocytic leukemia (CLL) were obtained in a highly purified state from a therapeutic leukapheresis preparation. The CLL lymphocytes showed a fine, scattered, granular pattern of nonspecific esterase cytochemical reactivity with either alpha-naphthyl acetate
J Yourno et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(6), 727-733 (1986-06-01)
Monocytes contain a characteristic, prominent set of membrane-bound nonspecific esterases with a slightly acid isoelectric point. These esterases are also detected at modest levels in some granulocyte preparations. They are not apparent in lymphocytes. Among 18 fresh myeloid leukemias and
Y Kaneko et al.
Blood, 60(2), 389-399 (1982-08-01)
We studied the karyotype in 26 children with ANLL, which was diagnosed on the basis of the FAB classification. Clonal chromosome abnormalities were found in 21 of 26 patients. Four patients, including 3 with Down's syndrome, had AML(M1). Nine patients
Esterases of the flounder (Platichthys flesus, Pleuronectidae, Teleostei): development of an identification protocol using starch gel electrophoresis and characterization of loci
Berrebi P, et al.
Experientia, 46(8), 863-867 (1990)
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