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Safety Information

N7756

Sigma-Aldrich

N-Nitrosodimethylamine

Synonym(s):

Dimethylnitrosamine

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About This Item

Linear Formula:
(CH3)2NNO
CAS Number:
62-75-9
Molecular Weight:
74.08
EC Number:
200-549-8
MDL number:
MFCD00002053
UNSPSC Code:
12352200
PubChem Substance ID:
24897837

vapor pressure

5 mmHg ( 20 °C)

description

Bulk package

refractive index

n20/D 1.437 (lit.)

bp

153 °C/774 mmHg (lit.)

density

1.01 g/mL (lit.)

storage temp.

2-8°C

SMILES string

CN(C)N=O

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

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Biochem/physiol Actions

Induces gastric, liver, kidney and lung cancer in mice and rats.

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Carc. 1B - STOT RE 1

Target Organs

Liver

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

141.8 °F - closed cup

Flash Point(C)

61.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
037K1594
122K0391
102K1081
101K0182
084K1066

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Yu Peng et al.
European journal of clinical investigation, 43(4), 358-368 (2013-02-27)
Fluorofenidone (AKF-PD) is a novel pyridone agent. The purpose of this study is to investigate the inhibitory effects of AKF-PD on dimethylnitrosamine (DMN)-induced liver fibrosis in rats and the involved molecular mechanism related to hepatic stellate cells (HSCs). Wistar rats
Man-Chun Huang et al.
Food chemistry, 138(1), 227-233 (2012-12-26)
A sensitive procedure, microwave-assisted extraction (MAE) coupled dispersive micro solid-phase extraction (D-μ-SPE), was developed to extract N-nitrosodimethylamine (NDMA) and other six volatile N-nitrosamines (NAms) from meat products. Parameters affecting the efficiency of MAE and D-μ-SPE were systematically investigated. For MAE
Maria José Farré et al.
Environmental science & technology, 46(23), 12904-12912 (2012-11-09)
UV-C radiation is the U.S. EPA recommended technology to remove N-nitrosodimethylamine (NDMA) during drinking and recycled water production. Frequently, H(2)O(2) is added to the treatment to remove other recalcitrant compounds and to prevent NDMA reformation. However, the transformation of NDMA
Ruqiao Shen et al.
Water research, 47(7), 2446-2457 (2013-03-05)
The presence of N-nitrosodimethylamine (NDMA) in drinking water is most commonly associated with the chloramination of amine-based precursors. One option to control the NDMA formation is to remove the precursors via pre-oxidation, and prechlorination is among the most effective options
Ina Kristiana et al.
Water research, 47(2), 535-546 (2012-11-21)
N-Nitrosamines are a class of disinfection by-products (DBPs) that have been reported to be more toxic than the most commonly detected and regulated DBPs. Only a few studies investigating the formation of N-nitrosamines from disinfection of natural waters have been
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