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Safety Information

N4165

Sigma-Aldrich

Neuroendocrine Regulatory Peptide-1 (human)

Synonym(s):

NERP-1 (Human)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

form

lyophilized powder

Quality Level

200

color

white

solubility

water, double-distilled: soluble

storage temp.

−20°C

Amino Acid Sequence

H-Arg-Pro-Glu-Ser-Ala-Leu-Leu-Gly-Gly-Ser-Glu-Ala-Gly-Glu-Arg-Leu-Leu-Gln-Gln-Gly-Leu-Ala-Gln-Val-Glu-Ala-NH2

General description

NERP1/2 peptides are responsible to a variety of physiological processes:
a. Modulation of body fluid homeostasis.
b. Suppression of basal and angiotensin II-induced vasopressin release from hypothalamic organ.
c. They were shown to evoke calcium responses in the pituitary gland and hypothalamus.

Physical form

Lyophilized from 0.1% aqueous TFA

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
122M4803V
122M4802V

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K Toshinai et al.
Cellular and molecular life sciences : CMLS, 66(11-12), 1939-1945 (2009-02-06)
Neuroendocrine regulatory peptides (NERP)-1 and NERP-2 are derived from distinct regions of VGF, a neurosecretory protein that was originally identified as a product of a nerve growth factor-responsive gene in rat PC12 cells. The amino acid length of human NERP-1
Takashi Matsuo et al.
Regulatory peptides, 163(1-3), 43-48 (2010-05-18)
Neuroendocrine regulatory peptides NERP-1 and NERP-2 are novel amidated peptides derived from VGF, a polypeptide secreted from neurons and endocrine cells through a regulated pathway. To explore the localization of NERPs in human tissues, we performed immunohistochemistry analysis on tissues

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