N3877
Potassium 4-nitrophenyl sulfate
sulfatase substrate, chromogenic, ≥98% (TLC), powder
Synonym(s):
4-Nitrophenyl sulfate potassium salt
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About This Item
Linear Formula:
NO2C6H4OSO2OK
CAS Number:
Molecular Weight:
257.26
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
228-288-5
MDL number:
Beilstein/REAXYS Number:
3786392
Product Name
Potassium 4-nitrophenyl sulfate, sulfatase substrate
Quality Level
assay
≥98% (TLC)
form
powder
mp
246-250 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)
shipped in
wet ice
storage temp.
−20°C
SMILES string
[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1
InChI
1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1
InChI key
BITVAZYUWRLLCN-UHFFFAOYSA-M
General description
Chromogenic sulfatase substrate.
Application
Potassium 4-nitrophenyl sulfate has been used:
- as a substrate to measure arylsulfatase activity in cell-free coelomic fluid
- as a substrate for p-nitrophenyl glycoside-based enzyme assay
- to inhibit arylsulfatase
- as an inorganic analog of organic aryl ester sulphate
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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H X Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 473-477 (1991-03-01)
Although numerous previous reports have characterized the mammalian biotransformation of the organophosphorus insecticides parathion and methyl parathion, questions still remain regarding the toxicological significance of certain metabolic pathways in vivo. The present study utilized rat liver perfusions in order to
N Sakuma-Sawada et al.
Research communications in molecular pathology and pharmacology, 97(2), 131-138 (1997-08-01)
Hepatic uptake of the sulfate conjugate of p-nitrophenol (p-NPsul) has been studied. Uptake clearance of p-NPsul by isolated rat hepatocytes was dependent on p-NPsul concentration, suggesting carrier-mediated transport. The uptake of p-NPsul by isolated rat hepatocytes was inhibited by acetaminophen
J O Falkinham
International journal of systematic bacteriology, 40(1), 66-70 (1990-01-01)
A rapid (3-h) arylsulfatase assay for cell suspensions of mycobacteria, in which p-nitrophenyl sulfate is used as the substrate, was developed. Arylsulfatase activity was found in cell suspensions of representative strains of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum grown
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N3877-1G | 04061835506477 |
| N3877-5G | 04061835506484 |
| N3877-500MG | 04061834116325 |