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Safety Information

N3632

Sigma-Aldrich

N-Nitrosodimethylamine

ISOPAC®

Synonym(s):

Dimethylnitrosamine

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About This Item

Linear Formula:
(CH3)2NNO
CAS Number:
62-75-9
Molecular Weight:
74.08
EC Number:
200-549-8
MDL number:
MFCD00002053
UNSPSC Code:
12352200
PubChem Substance ID:
24897656

vapor pressure

5 mmHg ( 20 °C)

refractive index

n20/D 1.437 (lit.)

bp

153 °C/774 mmHg (lit.)

density

1.01 g/mL (lit.)

storage temp.

2-8°C

SMILES string

CN(C)N=O

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

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Biochem/physiol Actions

Induces gastric, liver, kidney and lung cancer in mice and rats.

Packaging

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Caution

OSHA′s Safety and Health Standard 29 CFR 1910 does not apply to a solution or mixture containing less than 1%. Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Carc. 1B - STOT RE 1

Target Organs

Liver

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

141.8 °F - closed cup

Flash Point(C)

61.0 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
077K1186
026K1089
104K0656
101K01821
038F08822

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A Iwaniuk et al.
Human & experimental toxicology, 34(6), 591-600 (2014-10-12)
N-nitrosodimethylamine (NDMA) is a xenobiotic widespread in human environment capable of regulating the lifespan of immune cells. In this study, we examined the roles of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/death receptor 5 (DR5) complex and the Fas molecule

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