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N3288

Sigma-Aldrich

(+)-Norfenfluramine hydrochloride

≥98% (HPLC), powder

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Synonym(s):
JP 92, NSC 43036, S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride
Empirical Formula (Hill Notation):
C10H12F3N · HCl
CAS Number:
37936-89-3
Molecular Weight:
239.67
MDL number:
MFCD11045299
UNSPSC Code:
12352116
PubChem Substance ID:
329818604
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

storage condition

desiccated

color

white

solubility

H2O: >10 mg/mL

storage temp.

2-8°C

SMILES string

Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F

InChI

1S/C10H12F3N.ClH/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13;/h2-4,6-7H,5,14H2,1H3;1H/t7-;/m0./s1

InChI key

PIDLOFBRTWNFAR-FJXQXJEOSA-N

Biochem/physiol Actions

(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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