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N1377

Sigma-Aldrich

4-Nitrophenyl α-D-glucopyranoside

chromogenic, ≥99%, powder or crystals

Synonym(s):

p-Nitrophenyl α-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C12H15NO8
CAS Number:
3767-28-0
Molecular Weight:
301.25
Beilstein:
92212
EC Number:
223-189-3
MDL number:
MFCD00064088
UNSPSC Code:
12352204
PubChem Substance ID:
24897484
NACRES:
NA.32

Product Name

4-Nitrophenyl α-D-glucopyranoside, ≥99%

Quality Level

300

Assay

≥99%

form

powder or crystals

solubility

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChI key

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N

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Application

4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.

Biochem/physiol Actions

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL9702
BCCK8164
BCCH4822
BCCJ7239
BCCG4026

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the solubility of 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    We test the solubility of 4-Nitrophenyl α-D-glucopyranoside at 20 mg/mL in methanol.  When 4-Nitrophenyl α-D-glucopyranoside is used as a substrate for α-glucosidase, a 4 mM stock solution is made in water.

  4. What is the melting point and specific rotation for 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    The melting point range from our MSDS is 209-213 °C.  The optical rotation is lot specific, and can be found on the Certificate of Analysis at our website.

  5. How is 4-Nitrophenyl α-D-glucopyranoside, Product N1377, used?

    4-Nitrophenyl α-D-glucopyranoside is used as a substrate for the assay of α-glucosidase.  A stock solution of 4 mM is prepared in deionized water.  Upon the enzymatic hydrolysis of this substrate, 4-nitrophenol is produced.  The molar extinction coefficient of 4-nitrophenol in 0.01 M NaOH (pH 10.2) is approximately 18,380 at 400 nm. 

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

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