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Safety Information

MSST0064

Sigma-Aldrich

SILu™Prot Insulin, human

recombinant, expressed in Pichia pastoris, SIL MS Protein Standard, 15N -labeled

Synonym(s):

in situ Proximity Ligation Assay reagent, Insulin

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2.5 G
CN¥753.33
5 G
CN¥882.81
25 G
CN¥3,158.37
100 G
CN¥10,143.02

CN¥753.33

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2.5 G
CN¥753.33
5 G
CN¥882.81
25 G
CN¥3,158.37
100 G
CN¥10,143.02

About This Item

UNSPSC Code:
23201100
NACRES:
NA.32

CN¥753.33

Please contact Customer Service for Availability
Request a Bulk Order

recombinant

expressed in Pichia pastoris

Quality Level

200

Assay

≥95% (HPLC)

form

dry pellets

potency

≥97% (Heavy amino acids incorporation efficiency by MS)

suitability

suitable for mass spectrometry (standard)

UniProt accession no.

P01308 (25-54, B chain; 90-110, A chain)

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... INS(3630)

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Sodium cholate hydrate BioXtra, ≥99%

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Sodium cholate hydrate

Sodium deoxycholate monohydrate BioUltra, ≥99.0% (NT)

30968

Sodium deoxycholate monohydrate

aggregation number

1.9

aggregation number

6

aggregation number

2-3

aggregation number

3-12

description

anionic

description

anionic

description

anionic

description

anionic

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

mp

210-215 °C (subl.) (lit.)

mp

-

mp

-

mp

-

mol wt

micellar avg mol wt 900(lit.)

mol wt

micellar avg mol wt 3100

mol wt

micellar avg mol wt 900-1300

mol wt

average mol wt 1200-5000

General description

SILu™ Prot Insulin is a recombinant, stable 15N isotope-labeled human Insulin Expressed in P. pastoris, it is designed to be used as an internal standard for bioanalysis of Insulin in mass-spectrometry. SILu™ Prot Insulin is a disulfate bonded hetero-dimer protein composed of two chains. Chain A of 21 amino acids and a thoretical amolecular mass of 2408.5; Chain B of 30 amino acids and a thoretical amolecular mass of 3468.7 (Note that Thr30 in chain B is not 15N labeled).

Biochem/physiol Actions

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.

Sequence

A chain: GIVEQCCTSICSLYQLENYCN
B chain: FVNQHLCGSHLVEALYLVCGERGFFYTPKT

Physical form

Supplied as dried pellet from a solution containing 1% acetic acid.

Legal Information

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

胰岛素激素类产品
常规特殊物品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000411303
    0000411303
    0000310342
    0000310342
    0000212035

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