MAK296

Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric)

Name: Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric)
Brand: SIGMA

sufficient for 100 fluorometric tests

Synonym(s):

MAO-B Inhibitor Fluorometric Assay Kit

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About This Item

NACRES:

NA.25

UNSPSC Code:

12161503

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Product Name

Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric), sufficient for 100 fluorometric tests

detection method

fluorometric

relevant disease(s)

neurological disorders

storage temp.

−20°C

Application

Suitable for screening/studying/characterizing MAO-B inhibitors.

Biochem/physiol Actions

This MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H₂O₂, one of the byproducts generated during the oxidative deamination of the MAO substrate (tyramine).

Features and Benefits

Compatible with high-throughput handling systems.

General description

The new Monoamine Oxidase (MAO) Inhibitor Screening Kit, MAK520, is now available! Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A.