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MAK296

Sigma-Aldrich

Monoamine Oxidase-B Inhibitor Screening Kit (Fluorometric)

sufficient for 100 fluorometric tests

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Synonym(s):
MAO-B Inhibitor Fluorometric Assay Kit
UNSPSC Code:
12161503
NACRES:
NA.25

detection method

fluorometric

relevant disease(s)

neurological disorders

storage temp.

−20°C

General description

The new Monoamine Oxidase (MAO) Inhibitor Screening Kit, MAK520, is now available! Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A.

Features and Benefits

Compatible with high-throughput handling systems.

Suitability

Suitable for screening/studying/characterizing MAO-B inhibitors.

Principle

This MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of the MAO substrate (tyramine).

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

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