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MAK295

Sigma-Aldrich

Monoamine Oxidase-A Inhibitor Screening Kit (Fluorometric)

sufficient for 100 fluorometric tests

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.25

detection method

fluorometric

relevant disease(s)

neurological disorders

storage temp.

−20°C

General description

The new Monoamine Oxidase (MAO) Inhibitor Screening Kit, MAK520, is now available! Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A.

Features and Benefits

Compatible with high-throughput handling systems.

Suitability

Suitable for screening/studying/characterizing MAO-A inhibitors.

Principle

This MAO-A Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-A inhibitors. The assay is based on the fluorometric detection of hydrogen peroxide (H2O2), one of the by-products generated during the oxidative deamination of the MAO substrate (tyramine).

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

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