MAK293
Collagenase Activity Colorimetric Assay Kit
sufficient for 100 colorimetric tests
Synonym(s):
Collagenase Detection Kit
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.25
detection method
colorimetric
relevant disease(s)
cancer
storage temp.
−20°C
General description
Collagenase (EC 3.4.24.3) is an enzyme in the matrix metalloproteinase family that breaks down collagen, assisting in degradation of the extracellular matrix, a key step in the pathogenesis of bacteria. Collagen is an abundant structural protein present in the connective tissue of animals. Collagenase has been used clinically for the treatment of Dupuytren′s contracture, an affliction characterized by a thickening of connective tissue.
Suitability
Suitable for the measurement of collagenase activity in bacterial extract and for screening/studying/characterizing collagenase inhibitors in purified enzyme.
Principle
This Collagenase Activity Assay Kit provides a quick and easy way to determine activity of collagenase. The kit measures collagenase activity using a synthetic peptide (FALGPA) that mimics collagen′s structure. It is suitable for measuring activity of bacterial collagenases such as from Clostridium histolyticum. In addition, it can also be used to screen/characterize collagenase inhibitors. The limit of detection for this assay is 0.02 mU of collagenase.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
Regulatory Information
危险化学品
常规特殊物品
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