MAK244
Plasmin Activity Assay Kit (Fluorometric)
sufficient for 100 fluorometric tests
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Synonym(s):
Plasmin Fluorometric Assay Kit
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
detection method
fluorometric
relevant disease(s)
cancer; hematological disorder
storage temp.
−20°C
General description
Plasmin (EC 3.4.21.7) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasminogen-Plasmin system has also been implicated in a wide variety of physiologic and pathologic processes, including tumor growth, invasion and metastasis.
Suitability
Suitable to determine the activity of pure plasmin and to detect the activity of plasmin in plasma.
Principle
The Plasmin Activity Assay Kit is based on the ability of plasmin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. This assay kit is simple, rapid, and can detect plasmin activity as low as 10 ng in a variety of samples.
WGK
WGK 2
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Kwaan H C and McMahon B
Coagulation in Cancer, 43-66 (2009)
Goss N.
Production of Plasma Proteins for Therapeutic Use, 2012, 496 -496 null
Does plasmin have anticoagulant activity?.
Hoover-Plow J.
Vascular Health, 6, 199-199 (2010)
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