MAK080
Creatinine Assay Kit
sufficient for 100 colorimetric or fluorometric tests
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usage
sufficient for 100 colorimetric or fluorometric tests
detection method
colorimetric
fluorometric
relevant disease(s)
genitourinary disorders; neurological disorders
storage temp.
−20°C
General description
Creatinine is generated from creatine by nonenzymatic dehydration. Creatinine is produced at a constant rate and is excreted from the body through kidney glomerular filtration. Decreased kidney function can effect the rate at which creatinine is filtered by the kidneys and can be used as a measure of kidney function. Decreased kidney function can result in increased serum creatinine levels due to the inability to clear creatinine through urine excretion. Creatinine levels can be affected by changes in muscle mass, pregnancy, or the use of angiotensin inhibitors or angiotensin receptor antagonists.
Application
Creatinine Assay Kit has been used to measure the creatinine concentration in samples.
Suitability
Suitable for use with cell and tissue culture supernatants as well as serum, plasma, urine, and other biological fluids.
Principle
In this assay, Creatinine concentration is determined by a coupled enzyme reaction, which results in a colorimetric (570 nm)/fluorometric (λex = 535em/λ = 587 nm) product, proportional to the creatinine present.
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Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Resp. Sens. 1
WGK
WGK 3
Regulatory Information
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